Evaluation of depression and anxiety in patients with thalassemia: a comparative study

AR Haji SeyedJavadi; AA Shafikhani

Journal of Inflammatory Diseases

The Official Journal of Qazvin University of Medical Sciences

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Editors & Boards Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Publication Malpractice Statement Reviewer and AE Registration Form Support Contact Us

Authors Guide Submit Manuscript

Evaluation of depression and anxiety in patients with thalassemia: a comparative study

Author(s):

AR Haji SeyedJavadi^,*,

AA Shafikhani

Journal of Inflammatory Diseases:Vol. 21, issue 2; 21-13

Published online:Jul 31, 2017

Article type:Research Article

How to Cite:Haji SeyedJavadi A, Shafikhani A. Evaluation of depression and anxiety in patients with thalassemia: a comparative study. J Inflamm Dis. 2024;21(2):e156016. doi:

Abstract

Background: More studies in the field of thalassemia patients focus on medical treatment and less attention to the psychosocial problems aspect. Objective: The aim of this study was evaluation of depression and anxiety in these patients in Qazvin province. Methods: This case-control study has been conducted in Qods Hospital of Qazvin (2016). The study population included thalassemia major patients and control group were participating in this study (n=147 in each group). All subjects completed the hospital anxiety and depression scale (HADS). In addition to clinical history, socioeconomic and demographic characteristics of patients collected and analyzed using proper statistical methods independent t-test, chi-square test. Findings: Borderline abnormal (borderline case) and abnormal states of anxiety were reported 27.2% and 42.2% in case group compared with 22.4% and 6.8% in the control group (P<0.001). In addition, borderline and abnormal states of depression were significantly different in the case group than the control group (respectively 20.4% and 59.2% vs 24.5% and 12.9%, P<0.001). Among patients with thalassemia, depression and anxiety scores significantly were associated with non-compliance and iron chelation, marital status (single) and socioeconomic state (P<0.001). In addition, Moreover, in terms of depression individuals with diabetes, headaches and skin disorders significantly were higher scores of depression and in terms of anxiety individuals with low back pain, headaches and skin disorders were higher scores. Conclusion: The prevalence of depression and anxiety in patients with thalassemia is considerable and related to socioeconomic and demographic characteristics, so it is essential that psychiatric consultation systems created in thalassemia clinics of Qazvin province.

Keywords

Thalassemia

Depression

Anxiety

Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study

Fatemeh Behdani,

Zahra Badiee,

Paria Hebrani,

Fatemeh Moharreri,

Amir Hossein Badiee,

Negin Hajivosugh

,et al.

Behdani F, Badiee Z, Hebrani P, Moharreri F, Badiee AH, et al. Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study. Inn J Pediatr. 2015;25(3):-. doi: https://doi.org/10.5812/ijp.25(3)2015.322

30

Jun

2025

Socioeconomic Challenges of Adult Thalassemia Major Patients in Iran: A Cross-Sectional Study on Education, Employment, and Marital Status

Ghasem Miri-Aliabad,

Ali Khajeh,

Saeed Ghavi,

Neda Ashayeri,

Nahimeh Shahraki,

Masoome Fadaee

Miri-Aliabad G, Khajeh A, Ghavi S, Ashayeri N, Shahraki N, et al. Socioeconomic Challenges of Adult Thalassemia Major Patients in Iran: A Cross-Sectional Study on Education, Employment, and Marital Status. Zahedan J Res Med Sci. 2025;27(3):e163538. doi: https://doi.org/10.5812/zjrms-163538

8

Jan

2013

Prevalence of Diabetes and Impaired Glucose Tolerance Test in Patients with Thalassemia Major

Mehdi Jahantigh,

Majid Naderi,

Akbar Dorgalaleh,

Shadi Tabibian

Jahantigh M, Naderi M, Dorgalaleh A, Tabibian S. Prevalence of Diabetes and Impaired Glucose Tolerance Test in Patients with Thalassemia Major. Zahedan J Res Med Sci. 2013;16(1):e1763. doi:

10

Feb

2018

Hypothyroidism and Hypoparathyroidism in Thalassemia Major Patients: A Study in Sistan and Baluchestan Province, Iran

Ali Bazi,

Hadi Harati,

Ali Khosravi-Bonjar,

Elham Rakhshani,

Mojtaba Delaramnasab

Bazi A, Harati H, Khosravi-Bonjar A, Rakhshani E, Delaramnasab M. Hypothyroidism and Hypoparathyroidism in Thalassemia Major Patients: A Study in Sistan and Baluchestan Province, Iran. Int J Endocrinol Metab. 2018;16(2):e13228. doi: https://doi.org/10.5812/ijem.13228

25

Aug

2015

Evaluation of marriage and childbirth in patients with non-transfusion-dependent beta thalassemia major at Thalassemia Research Center of Sari, Iran

Mandana Zafari,

Mehnoush Kowsarian

Zafari M, Kowsarian M. Evaluation of marriage and childbirth in patients with non-transfusion-dependent beta thalassemia major at Thalassemia Research Center of Sari, Iran. J Nurs Midwifery Sci. 2015;2(2):e141299. doi: https://doi.org/10.7508/jnms.2015.02.005

Import into EndNote Import into BibTex

Share on

Comments

Number of Comments:0

Cited by

Scopus by DOI: 0
Last Update: 1 month ago
Scopus by Title: 0
Last Update: 1 month ago
Scopus by Title (Ref): 4
Last Update: 1 month ago
CrossRef: 0
Last Update: 4 days ago

Metrics

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC

Search Relations

Author(s):

AR Haji SeyedJavadi:[PubMed][Scholar]
AA Shafikhani:[PubMed][Scholar]

The Official Journal of Qazvin University of Medical Sciences

Outlines

Evaluation of depression and anxiety in patients with thalassemia: a comparative study

Abstract

Similar Articles

Psychological Aspects in Children and Adolescents With Major Thalassemia: A Case-Control Study

Socioeconomic Challenges of Adult Thalassemia Major Patients in Iran: A Cross-Sectional Study on Education, Employment, and Marital Status

Prevalence of Diabetes and Impaired Glucose Tolerance Test in Patients with Thalassemia Major

Hypothyroidism and Hypoparathyroidism in Thalassemia Major Patients: A Study in Sistan and Baluchestan Province, Iran

Evaluation of marriage and childbirth in patients with non-transfusion-dependent beta thalassemia major at Thalassemia Research Center of Sari, Iran

Last Update: 1 month ago

Last Update: 1 month ago

Last Update: 1 month ago

Last Update: 4 days ago