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Jentashapir Journal of Cellular and Molecular Biology
Official Journal of Ahvaz Jundishapur University of Medical Sciences
e-ISSN 2717-2724
Study on the seroprevalence of hepatitis E virus infection in pregnant women referring to Imam Khomeini general hospital in Ahvaz
Authors
Mojtaba Rasti1, Alireza Samarbafzadeh2, Niloofar Neisi
3,*, Manoochehr Makvandi4, Saeed Najafifard5, Moosa Sharifat6, Mahvash Zargar7
3,*, Manoochehr Makvandi4, Saeed Najafifard5, Moosa Sharifat6, Mahvash Zargar71M.Sc. of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center, Department of Virology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran.
2Associated Professor of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center, Department of Virology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran.
3Ph.D. Student of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center and Research Institute for Infectious Diseases of Digestive System, Deptartment of Virology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran
4Professor of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center and Research Institute for Infectious Diseases of Digestive System, Deptartment of Virology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran
5M.Sc. of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center, Department of Virology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran
6B.Sc. of Laboratory Sciences, Department of Pharmacology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran
7Assistant Professor of Obstetrics and gynaecology, Department of Obstetrics and Gynaecology, Imam Khomeini Hospital, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
*Corresponding Author: Ph.D. Student of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center and Research Institute for infectious Diseases of Digestive System, Department of Virology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran. Tel:+986113738313 Email: niloofarneisi@yahoo.com
Published online:May 13, 2013
Article type:Research Article
How to Cite:Rasti M, Samarbafzadeh A, Neisi N, Makvandi M, Najafifard S, et al. Study on the seroprevalence of hepatitis E virus infection in pregnant women referring to Imam Khomeini general hospital in Ahvaz. Jentashapir J Cell Mol Biol. 2014;5(3):. doi:
Abstract
Regarding to fecal- oral transmission of hepatitis E virus and risk of fulminant hepatitis in the third trimester of pregnancy, the aim of the present study was to determine seroprevalence of HEV in pregnant women with regard to age, level of education, trimester of pregnancy and residency.
A total of 418 serum samples were collected from January 2010 to January 2011. All pregnant women filled out the questionnaire form. Serum samples were examined for anti-HEV IgG and anti- HEV IgM using ELISA method.
From 418 women, 22 cases were positive for anti-HEV IgG (5.26%) and in one woman (0.23%) anti- HEV IgM was positive. In the age groups of 30-40 and 20-30 years, the seropositivity for anti-HEV IgG was 8.6% and 2.5%, respectively. In group with higher age the positive cases of anti-HEV IgG was higher than in the other group. The rate of positivity of anti-HEV IgG in pregnant women with low level of education was 11.4% whereas 3% in university educated women. There was a significant difference between seropositivity of anti-HEV IgG and the trimester of pregnancy. The most of anti-HEV IgG positive were occurred in the third trimester of pregnancy (8.6%).Out of this 22 anti-HEV IgG positive cases 4.4% were living in urban and 6.3% were in rural areas.
Regarding to fecal- oral transmission of hepatitis E virus and risk of fulminant hepatitis in the third trimester of pregnancy, the aim of the present study was to determine seroprevalence of HEV in pregnant women with regard to age, level of education, trimester of pregnancy and residency.
A total of 418 serum samples were collected from January 2010 to January 2011. All pregnant women filled out the questionnaire form. Serum samples were examined for anti-HEV IgG and anti- HEV IgM using ELISA method.
From 418 women, 22 cases were positive for anti-HEV IgG (5.26%) and in one woman (0.23%) anti- HEV IgM was positive. In the age groups of 30-40 and 20-30 years, the seropositivity for anti-HEV IgG was 8.6% and 2.5%, respectively. In group with higher age the positive cases of anti-HEV IgG was higher than in the other group. The rate of positivity of anti-HEV IgG in pregnant women with low level of education was 11.4% whereas 3% in university educated women. There was a significant difference between seropositivity of anti-HEV IgG and the trimester of pregnancy. The most of anti-HEV IgG positive were occurred in the third trimester of pregnancy (8.6%).Out of this 22 anti-HEV IgG positive cases 4.4% were living in urban and 6.3% were in rural areas.
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© 2014, Jentashapir Journal of Cellular and Molecular Biology. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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