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Jundishapur Journal of Microbiology
Ahvaz Jundishapur University of Medical Sciences
e-ISSN 2008-4161
p-ISSN 2008-3645
Comparative evaluation of three and six month therapeutic regimens for smear negative pulmonary tuberculosis
Authors
1Infectious and Tropical Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences, alavi1329dr@yahoo.com, Iran
*Corresponding Author: Infectious and Tropical Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences, alavi1329dr@yahoo.com, Iran. Email: alavi1329dr@yahoo.com
Published online:Jan 31, 2009
Article type:Research Article
Received:Nov 01, 2008
Accepted:Jan 01, 2009
How to Cite:Alavi SM. Comparative evaluation of three and six month therapeutic regimens for smear negative pulmonary tuberculosis. Jundishapur J Microbiol. 2009;2(1):. doi:
Abstract
Both smears positive and negative Pulmonary Tuberculosis (PTB) patients are routinely treated by six month therapeutic regimen. The aim of this study was to compare three and six month regimens chemotherapy for smear negative PTB among tuberculosis patients. Fifty-two patients with smear negative PTB randomly divided into two groups took part in this comparative clinical trial study. The patients in first group were treated with our recommended regimen (rifampicin, isoniazide, and ofloxacin) and another group with standard regimen according directly observed treatment short course strategy. Cure rates in first and second group were 96.5% and 100% respectively. There was no difference between two groups in responding to anti tuberculosis chemotherapy (p>0.05). This study showed that three month therapeutic regimen is as effective as six month therapeutic regimen and may be considered effective treatment for adult patients with unprogressive smear negative PTB.
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© 2009, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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