Full Text
Full text is available in PDF
Jundishapur Journal of Microbiology
Ahvaz Jundishapur University of Medical Sciences
Comparative evaluation of three and six month therapeutic regimens for smear negative pulmonary tuberculosis
Author(s):
1Infectious and Tropical Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences, [email protected], Iran
*Corresponding Author: Infectious and Tropical Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences, [email protected], Iran. Email: [email protected]
Published online:Jan 31, 2009
Article type:Research Article
Received:Nov 01, 2008
Accepted:Jan 01, 2009
How to Cite:Alavi SM. Comparative evaluation of three and six month therapeutic regimens for smear negative pulmonary tuberculosis. Jundishapur J Microbiol. 2009;2(1):. doi:
Abstract
Both smears positive and negative Pulmonary Tuberculosis (PTB) patients are routinely treated by six month therapeutic regimen. The aim of this study was to compare three and six month regimens chemotherapy for smear negative PTB among tuberculosis patients. Fifty-two patients with smear negative PTB randomly divided into two groups took part in this comparative clinical trial study. The patients in first group were treated with our recommended regimen (rifampicin, isoniazide, and ofloxacin) and another group with standard regimen according directly observed treatment short course strategy. Cure rates in first and second group were 96.5% and 100% respectively. There was no difference between two groups in responding to anti tuberculosis chemotherapy (p>0.05). This study showed that three month therapeutic regimen is as effective as six month therapeutic regimen and may be considered effective treatment for adult patients with unprogressive smear negative PTB.
Copyright
© 2009, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
31
Jul
2017
The Follow-up of 360 Patients with Pulmonary Tuberculosis After 2 Months Treatment With Anti-tubercular Agents in Iran
Marzieh Kazerani,
Maryam Kazerani,
Kiarash Ashrafzadeh,
Shamim Rahiman,
Mahdi Mottaghy,
Amin Samihi
Kazerani M, Kazerani M, Ashrafzadeh K, Rahiman S, Mottaghy M, et al. The Follow-up of 360 Patients with Pulmonary Tuberculosis After 2 Months Treatment With Anti-tubercular Agents in Iran. Arch Clin Infect Dis. 2018;13(4):e62132. doi: https://doi.org/10.5812/archcid.62132
1
Feb
2014
Comparison of Culture and PCR Methods for Diagnosis of Mycobacterium tuberculosis in Different Clinical Specimens
Aida Gholoobi,
Ali Masoudi-Kazemabad,
Mojtaba Meshkat,
Zahra Meshkat
Gholoobi A, Masoudi-Kazemabad A, Meshkat M, Meshkat Z. Comparison of Culture and PCR Methods for Diagnosis of Mycobacterium tuberculosis in Different Clinical Specimens. Jundishapur J Microbiol. 2014;7(2):e8939. doi: https://doi.org/10.5812/jjm.8939
17
Apr
2013
A Seven Year Retrospective Study on Epidemiology and Clinical Characteristics of Tuberculosis in Iran
Simindokht Bayat,
Ali Gol-Mohamadi,
Mohamad Reza Sarbazi,
Azadeh Safaee,
Ahmad Reza Farsar
Bayat S, Gol-Mohamadi A, Sarbazi MR, Safaee A, Farsar AR. A Seven Year Retrospective Study on Epidemiology and Clinical Characteristics of Tuberculosis in Iran. Arch Clin Infect Dis. 2013;8(2):ee14505. doi: https://doi.org/10.5812/archcid.14505
23
Sep
2014
Comparison of Chest X-Ray Findings of Smear Positive and Smear Negative Patients with Pulmonary Tuberculosis
Azadeh Ebrahimzadeh,
Mahyar Mohammadifard,
Godratallah Naseh
Ebrahimzadeh A, Mohammadifard M, Naseh G. Comparison of Chest X-Ray Findings of Smear Positive and Smear Negative Patients with Pulmonary Tuberculosis. I J Radiol. 2014;11(4):e13575. doi: https://doi.org/10.5812/iranjradiol.13575
30
Aug
2023
Comparison of the Severity of Lung Damage on Chest X-ray Between New Drug-Resistant and Drug-Sensitive Cases of Pulmonary Tuberculosis Patients
Soedarsono Soedarsono,
Alvian Fauzi,
Anita Widyoningroem,
Ni Made Mertaniasih
Soedarsono S, Fauzi A, Widyoningroem A, Mertaniasih NM. Comparison of the Severity of Lung Damage on Chest X-ray Between New Drug-Resistant and Drug-Sensitive Cases of Pulmonary Tuberculosis Patients. Arch Clin Infect Dis. 2023;18(3):e137113. doi: https://doi.org/10.5812/archcid-137113
Download PDF727.32 KB
Comments
Number of Comments:0Cited by
- Scopus by DOI: 0
Last Update: 0 months ago
- Scopus by Title: 3
Last Update: 0 months ago
- Scopus by Title (Ref): 3
Last Update: 0 months ago
- CrossRef: 0
Last Update: 5 days ago
Ordering Reprints
Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC
Search Relations
Related Articles