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Jundishapur Journal of Microbiology
Ahvaz Jundishapur University of Medical Sciences
Phospholipase activity of Candida albicans isolated from vagina and urine samples
Author(s):
1Infectious and Tropical Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences-Department of Medical Mycoparasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, [email protected], Iran
2Department of Medical Mycoparasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Iran
*Corresponding Author: Infectious and Tropical Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences-Department of Medical Mycoparasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, [email protected], Iran. Email: [email protected]
Published online:Oct 31, 2010
Article type:Research Article
Received:May 01, 2010
Accepted:Jun 01, 2010
How to Cite:Zarei Mahmoudabadi A, Zarrin M, Miry S. Phospholipase activity of Candida albicans isolated from vagina and urine samples. Jundishapur J Microbiol. 2010;3(4):. doi:
Abstract
Introduction and objective: Candida albicans is the most virulent among the Candida species, and can cause several forms of candidiasis in human. Extracellular phospholipases in C. albicans is discussed as one of the virulence factors. The present study, focused on extracellular phospholipase activities in different isolates of C. albicans isolated from vagina and urine samples from Ahvaz, Iran. In addition, phospholipase activities were compared in C. albicans isolated from two different sources.
Materials and methods: In the present study, phospholipase activity of 100 isolates of C. albicans with urine and vaginitis origin was demonstrated using Sabouraud's dextrose agar supplemented with egg yolk.
Results: The phospholipase activity was detected in all tested isolates with a high level in Pz<0.70. In the present study phospholipase activity with higher Pz values was more common in vaginal isolates (84.7% isolates with Pz value <0.70) compared with 75% in urine isolates.
Conclusion: In the present study, 100% clinical isolates of C. albicans from vaginitis and urine samples demonstrated phospholipase activity.
Copyright
© 2010, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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