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56 resultsUpdated October 25, 2026
1

Saffron: a promising natural medicine in the treatment of metabolic syndrome

Journal of the Science of Food and Agriculture 97(6) (2016)

Bibi Marjan Razavi; Hossein Hosseinzadeh

2

The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents

Oxidative Medicine and Cellular Longevity 2022(1) (2022)

Monica Butnariu; Cristina Quispe; Jesús Herrera‐Bravo; Javad Sharifi‐Rad; Laxman Singh; Nora M. Aborehab; Abdelhakim Bouyahya; Alessandro Venditti; Surjit Sen; Krishnendu Acharya; Moein Bashiry; Shahira M. Ezzat; William N. Setzer; Miquel Martorell; Ksenija S. Mileski; Iulia Cristina Bagiu; Anca Oana Docea; Daniela Cornelia Călina; William Chi Shing Cho

4

Antioxidant Properties of Crocus Sativus L. and Its Constituents and Relevance to Neurodegenerative Diseases; Focus on Alzheimer’s and Parkinson’s Disease

Current Neuropharmacology 17(4) (2018)

Kyriaki Hatziagapiou; Eleni Kakouri; George Ι. Lambrou; Kostas Bethanis; Petros Α. Tarantilis

5

Heat stress-induced neuroinflammation and aberration in monoamine levels in hypothalamus are associated with temperature dysregulation

Neuroscience 358 (2017)

Nishant Ranjan Chauhan; Medha Kapoor; Laxmi Prabha Singh; Rajinder Kumar Gupta; Ramesh Chand Meena; Rajkumar Tulsawani; Sarita Nanda; Shashi Bala Singh

6

Saffron and its derivatives, crocin, crocetin and safranal: a patent review

Expert Opinion on Therapeutic Patents 28(2) (2017)

Maryam Rameshrad; Bibi Marjan Razavi; Hossein Hosseinzadeh

7

Saffron with resistance exercise improves diabetic parameters through the GLUT4/AMPK pathway in-vitro and in-vivo

Scientific Reports 6(1) (2016)

Firouzeh Dehghan; Fatemeh Hajiaghaalipour; Ashril Yusof; Sekaran Muniandy; Seyed Ali Hosseini; Sedigheh Heydari; Landa Zeenelabdin Ali Salim; Mohammad Ali Azarbayjani

8

Clinical evidence on the effects of saffron (Crocus sativus L.) on cardiovascular risk factors: A systematic review meta-analysis

Pharmacological Research 139 (2018)

Makan Pourmasoumi; Amir Hadi; Ameneh Najafgholizadeh; Marzieh Kafeshani; Amirhossein Sahebkar

9

Effects of saffron (Crocus sativus L.) supplementation on cardiometabolic Indices in diabetic and prediabetic overweight patients: a systematic review and meta-analysis of RCTs

Diabetology & Metabolic Syndrome 16(1) (2024)

Mehdi Karimi; Samira Pirzad; Niyousha Shirsalimi; Mohammad Hossein Hosseini; Pouya Ebrahimi; Sara Khoshdooz; Pegah Rashidian

10

Saffron as an antidote or a protective agent against natural or chemical toxicities

DARU Journal of Pharmaceutical Sciences 23(1) (2015)

Bibi Marjan Razavi; Hossein Hosseinzadeh

11

The effect of saffron (Crocus sativus L.) hydroalcoholic extract on metabolic control in type 2 diabetes mellitus: A triple-blinded randomized clinical trial

Journal of Research in Medical Sciences 23(1) (2018)

Abolghassem Djazayeri; Shahin Akhondzadeh; Alireza Milajerdi; Shima Jazayeri; Najmeh Hashemzadeh; Elham Shirzadi; Zhaleh Derakhshan

12

Possible Role of Common Spices as a Preventive and Therapeutic Agent for Alzheimer's Disease

International Journal of Preventive Medicine 8(1) (2017)

Omid Mirmosayyeb; Amir Pouya Tanhaei; Hamid Reza Sohrabi; Ralph Nigel Martins; Mana Tanhaei; Mohammad Amin Najafi; Ali Safaei; Rokhsareh Meamar

14

Saffron against Components of Metabolic Syndrome: Current Status and Prospective

Journal of Agricultural and Food Chemistry 65(50) (2017)

Mojtaba Shafiee; Nazanin Sadat Aghili‐Moghaddam; Mohammad Nosrati‐Oskouie; M. Seilanian Tousi; Amir Avan; Mikhail Ryzhikov; Mohammad Reza Parizadeh; Hamid Fiuji; Majid Rajabian; Amirhossein Bahreyni; Majid Khazaei; Seyed Mahdi Hassanian

15

Current Knowledge of the Antidepressant Activity of Chemical Compounds from Crocus sativus L.

Pharmaceuticals 16(1) (2022)

Renata Matraszek; Mirosława Chwil; Karol Terlecki; Michał Marian Skoczylas

16

Effects of Crocetin Esters and Crocetin from Crocus sativus L. on Aortic Contractility in Rat Genetic Hypertension

Molecules 20(9) (2015)

Sílvia Llorens; Andrea Mancini; Jéssica Serrano‐Díaz; Anna Maria D’Alessandro; Eduardo Nava; Gonzalo L. Alonso; Manuel Carmona

18

Chemoprevention effect of the Mediterranean diet on colorectal cancer: Current studies and future prospects

Frontiers in Nutrition 9 (2022)

Asma Ismail Mahmod; Shatha Khaled Haif; Ayah Kamal; Israa A. Al-ataby; Wamidh H. Talib

19

Cure and prevention of cardiovascular diseases: herbs for heart

Clinical Phytoscience 7(1) (2021)

Suman Ray; Mahesh Kumar Saini

20

Sniffing out adulteration in saffron: Detection methods and health risks

Food Control 155 (2023)

Ashish Raina; Sanjana Kaul; Manoj K. Dhar

21

Turmeric, Pepper, Cinnamon, and Saffron Consumption and Mortality

Journal of the American Heart Association 8(18) (2019)

Maryam Hashemian; Hossein Poustchi; Gwen A Murphy; Arash Etemadi; Farin Kamangar; Akram Pourshams; Masoud Khoshnia; Abdolsamad Gharavi; Paul Brennan; Paolo Boffetta; Sanford M. Dawsey; Christian C. Abnet; Reza Malekzadeh

22

Medicinal plants with cardiovascular effects (part 2): plant based review

IOSR Journal of Pharmacy (IOSRPHR) 06(07) (2016)

Ali Esmail Al‐Snafi

23

Potential of aqueous extract of saffron ( Crocus sativus L.) in blocking the oxidative stress by modulation of signal transduction in human vascular endothelial cells

Journal of Functional Foods 26 (2016)

Violeta Rodriguez‐Ruiz; Abolfazl Barzegari; Marisol Zuluaga Tamayo; Sepideh Zununi Vahed; Yalda Rahbar Saadat; Didier Letourneur; Virginie Gueguen; Graciela Pavon‐Djavid

24

Impact of Crocus sativus L. on Metabolic Profile in Patients with Diabetes Mellitus or Metabolic Syndrome: A Systematic Review

Nutrients 12(5) (2020)

Parthena Giannoulaki; Evangelia Kotzakioulafi; Michail Chourdakis; Apostolos Ioannis Hatzitolios; Triantafyllos Didangelos

25

The Relaxant Effect of Crocin on Rat Tracheal Smooth Muscle and Its Possible Mechanisms.

PubMed 18(3) (2019)

Saeideh Saeideh; Mahsa Yasavoli; Zahra Gholamnezhad; Mohammad Reza Aslani; Mohammad Hossein Boskabady

26

Crocin exhibits an antihypertensive effect in a rat model of gestational hypertension and activates the Nrf-2/HO-1 signaling pathway

Hypertension Research 44(6) (2021)

Xuan Chen; Jingying Huang; Yuchun Lv; Youfang Chen; Jinghong Rao

27

Anti‑hypertensive effect of crocin and hesperidin combination in high‑fat diet treated rats

Experimental and Therapeutic Medicine 19(6) (2020)

Mahmoud Hashemzaei; Ramin Rezaee; Mojtaba Nabatzehi; Konstantinos Tsarouhas; Τaxiarchis Κonstantinos Νikolouzakis; George Lazopoulos; Demetrios A. Spandidos; Aristidis Michael Tsatsakis; Jafar Shahraki

28

Clinical Evidence on the Effects of Saffron (Crocus Sativus L.) in Anxiety and Depression

World Journal of Traditional Chinese Medicine 8(2) (2021)

Vanktesh Kumar; Navjot Kaur; Pankaj K. Wadhwa

29

Crocin Effects on Human Myeloma Cells Regarding Intracellular Redox State, DNA Fragmentation, and Apoptosis or Necrosis Profile

Jundishapur Journal of Natural Pharmaceutical Products 9(4) (2014)

Ramin Rezaee; Khadijeh Jamialahmadi; Bamdad Riahi‐Zanjani; Mahmoud Mahmoudi; Khalil Abnous; Shahrzad Zamani Taghizadeh Rabe; Nafiseh Sadat Tabasi; Marjan Zali; Marjan Rezaee; Bahareh Amin; Gholamreza Karimi

30

Crocin restores the balance of Th1/Th2 immune cell response in ConA-treated human lymphocytes

Pharmacological Reports 74(3) (2022)

Hakimeh Abdi; Zahra Aganj; Hossein Hosseinzadeh; Fatemeh Mosaffa

32

Therapeutic potential of saffron, and its chemical components in the treatment of cancers and cardiovascular disorders – a review

International Food Research Journal 28(5) (2021)

Asif Khan; Nur Airina Muhamad; Rosna Mat Taha; Jamaludin Mohamad; Baker Al-Shara

33

Herbal Therapies for Weight Gain and Metabolic Abnormalities Induced by Atypical Antipsychotics: A Review Article

Current Drug Discovery Technologies 20(5) (2023)

Hamideh Naghibi; Roshanak Salari; Mahdi Yousefi; Majid Khadem‐Rezaiyan; Mohammad Reza Ghanbarzadeh; Mohammad Reza Fayyazı Bordbar

34

Therapeutic Potential of Saffron Crocus (Crocus sativus L.)

Turkish Journal of Agriculture - Food Science and Technology 4(12) (2016)

Zeliha Selamoğlu; Şenay Özgen

35

Medicinal plants for prevention and treatment of cardiovascular diseases - A review

IOSR Journal of Pharmacy (IOSRPHR) 07(04) (2017)

Ali Esmail Al‐Snafi

36

Saffron: A Therapeutic and Prophylactic Nutrition for Human Population

Springer eBooks (2021)

M. H. Khan; Bashir Ahmad Alie; Asif M. Iqbal Qureshi; G. H. Mir; Niyaz A. Dar; Shahid Qayoom; Tauseef Ali; Shabir Ahmad Dar; Ajaz Ahmad Lone; Z. A. Dar; Mushtaq Ahmad; M. Y. Bhat; Farooq Ahmad Sheikh

37

Saffron, its main derivatives, and their effects on the respiratory system

Elsevier eBooks (2020)

Mohammad-Hossein Boskabady; Vahideh Ghorani; Azam Alavinezhad

38

Crocus sativus L. (Saffron) and Its Components Relaxant Effect on Smooth Muscles and Clinical Applications of This Effect

Elsevier eBooks (2020)

Mohammad Hossein Boskabady; Amin Mokhtari‐Zaer; Mohammad Reza Khazdair; Arghavan Memarzia; Zahra Gholamnezhad

39

antioxidant and antihypertensive potential of Ledebouria hyderabadensis

International Journal of Health Sciences (2022)

E. Sujatha; B Soni Veenaa; T Sowmyya

40

Crocin-Induced Endothelium-Dependent Relaxation in Isolated Rat Aorta

Jundishapur Journal of Natural Pharmaceutical Products 12(2) (2016)

Bibi Marjan Razavi; Meysam Seydali Seyfabad; Hossein Hosseinzadeh; Mohsen Imenshahidi

41

Crocus sativus L. (Iridaceae)

Springer eBooks (2020)

Shahid Akbar

42

Spices and Hypertension: An Insight for Researchers

Current Nutrition & Food Science 18(3) (2021)

Kavyanjana R. Nair; Arya V.S.; S.K. Kanthlal; Uma Devi P.

43

Hypotensive and vascular activities of medicinal plants

GSC Biological and Pharmaceutical Sciences 19(3) (2022)

Ali Esmail Al‐Snafi

44

Effect of Crocus sativus L. (Saffron) on Selected Cardiometabolic Traits in Healthy Young Men

Iranian Journal of Public Health 51(7) (2022)

Wissal Abassi; Nejmeddine Ouerghi; Nidhal Jebabli; Moncef Feki; Anissa Bouassida

45

Study the Possible Protective Effect of Saffron Extract on Induced Rats Toxicity by Acrylamide

Egyptian Journal of Nutrition and Health 17(2) (2023)

Sara Mahmoud Moustafa Omar

46

Edible flowers as a source of bioactive compounds

Elsevier eBooks (2024)

Monroy-García Imelda Noehmi; González-Galván Laura Lucely; Ezequiel Viveros‐Valdez

47

Voltammetric study of saffron in blood mediated by modified glassy carbon electrode (GCE) with carbon nanotube (CNT/GCE)

Epitoanyag-Journal of Silicate Based and Composite Materials 70(3) (2018)

Muhammed Mizher Radhi; Maysara Samer Khalaf; Zainab Oun Ali; Thamir Aboud Al-Dabbagh

48

Effect of Saffron (Crocus sativus L) on Common NonCommunicable Disease: Review from Current Clinical Findings

Journal of Ayurvedic and Herbal Medicine 7(2) (2021)

Akibul Islam Chowdhury; Mohammad Asadul Habib; Susmita Ghosh

49

Unani perspective on COVID-19 and the possible role of Tiryaq Wabai in its management: A Review

Journal of Drug Delivery and Therapeutics 11(5) (2021)

Mohd. A. Aleem; Md Imran Khan; Mohd Danish; Qamrul Islam Usmani; Altaf Ahmad

50

Crocin-Induced Endothelium-Dependent Relaxation in Isolated Rat Aorta

Jundishapur Journal of Natural Pharmaceutical Products In Press(In Press) (2016)

Bibi Marjan Razavi; Meysam Seydali Seyfabad; Hossein Hosseinzadeh; Mohsen Imenshahidi

51

Clinical evidence on the effects of saffron (crocus sativus l.) in anxiety and depression

World Journal of Traditional Chinese Medicine 0(0) (2021)

Pankaj K. Wadhwa; Vanktesh Kumar; Navjot Kaur

52

Metabolite and bioactivity profiling of natural and elicitor-enhanced Crocus sativus L. extracts as a biotechnological source of antioxidants: in silico targeting of oxidative stress-related enzymes

Plant Cell Tissue and Organ Culture (PCTOC) 162(3) (2025)

Sümeyra Çetinkaya; Ülkü Selcen Haydaroğlu; Hasya Nazlı Gök; Pınar Nartop; Reyhan Bahtiyarca Bağdat; Firdevs Özbek; Kübra Ayaz; Serkan Uranbey