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25 resultsUpdated October 25, 2026
1

Crocin mediated amelioration of oxidative burden and inflammatory cascade suppresses diabetic nephropathy progression in diabetic rats

Chemico-Biological Interactions 284 (2018)

Hadeer O. Abou-Hany; Hoda Atef; Eman Said; Hassan A. Elkashef; Hatem A. Salem

2

A comprehensive review on regulatory effects of crocin on ischemia/reperfusion injury in multiple organs

Biomedicine & Pharmacotherapy 99 (2018)

Ghaidafeh Akbari; Seyyed ali Mard; Ali Veisi

3

The effects of prenatal androgen exposure on cardiac function and tolerance to ischemia/reperfusion injury in male and female rats during adulthood

Life Sciences 229 (2019)

Mahsa Noroozzadeh; Mohammad Reza Raoufy; Razieh Bidhendi Yarandi; Farzaneh Faraji Shahrivar; Fahimeh Ramezani Tehrani

4

Exogenous apelin changes alpha and beta myosin heavy chain mRNA expression and improves cardiac function in PTU-induced hypothyroid rats

Gene 595(1) (2016)

Farzaneh Faraji Shahrivar; Mohammad Badavi; Mahin Dianat; Ali Mard; Akram Ahangarpour; Alireza Samarbaf-zadeh

5

Moderating effects of crocin on some stress oxidative markers in rat brain following demyelination with ethidium bromide

Heliyon 5(2) (2019)

Hadi Fathimoghadam; Yaghoub Farbod; Ataallah Ghadiri; Rouholah Fatemi

7

Crocin protects cardiomyocytes against LPS-Induced inflammation

Pharmacological Reports 71(6) (2019)

Vafa Baradaran Rahim; Mohammad Taghi Khammar; Hassan Rakhshandeh; Alireza Samzadeh-Kermani; Azar Hosseini; Vahid Reza Askari

8

The apocarotenoid production in microbial biofactories: An overview

Journal of Biotechnology 374 (2023)

Ressin Varghese; Tinamoni Buragohain; Ishani Banerjee; Rishyani Mukherjee; Shraddha Naresh Penshanwar; Swapna Agasti; Siva Ramamoorthy

9

Analysis of Anti-Arrhythmic Impacts of Crocin through Estimation of Expression of Cx43 in Myocardial Infarction Using a Rat Animal Model

ACS Omega 7(42) (2022)

Huan Li; Jian Li; Juanli Wang; Obaid Afzal; Abdulmalik S. A. Altamimi; Shehla Nasar Mir Najib Ullah; Sireen Abdul Rahim Shilbayeh; Alnada Abdalla Ibrahim; Shahanavaj Khan

10

Crocin treatment prevents doxorubicin-induced cardiotoxicity in rats

Life Sciences 157 (2016)

Nasser Razmaraii; Hossein Babaei; Alireza Mohajjel Nayebi; Gholamreza Assadnassab; Javad Ashrafi Helan; Yadollah Azarmi

11

The Beneficial Effects of Saffron Extract on Potential Oxidative Stress in Cardiovascular Diseases

Oxidative Medicine and Cellular Longevity 2021(1) (2021)

Xin Su; Chao Yuan; Li Wang; Runqi Chen; Xiangying Li; Yijun Zhang; Can Liu; Xu Liu; Wanping Liang; Yanwei Xing; Guodong Zhang

12

Crocin modulates IL-4/IL-13 signaling and ameliorates experimentally induced allergic airway asthma in a murine model

International Immunopharmacology 50 (2017)

Haidy Yosri; Wagdi F. Elkashef; Eman Said; Nariman M. Gameil

13

The Impact of Vitamin E Supplementation on Oxidative Stress, Cognitive Functions, and Aging‐Related Gene Expression in Aged Mice

Food Science & Nutrition 12(11) (2024)

Farnoosh Molavi Vasei; Mohammad Yasin Zamanian; Maryam Golmohammadi; Mehdi Mahmoodi; Morteza Khademalhosseini; Tayyebeh Tavakoli; Ozra Sadat Esmaeili; Sadegh Zarei; Mohammad Reza Mirzaei; Mohammad Reza Hajizadeh

14

Treatment with crocin improves cardiac dysfunction by normalizing autophagy and inhibiting apoptosis in STZ-induced diabetic cardiomyopathy

Nutrition, Metabolism and Cardiovascular Diseases 28(9) (2018)

K. Feidantsis; K. Mellidis; E. Galatou; Z. Sinakos; A. Lazou

15

α-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury

Redox Biology 26 (2019)

Maria Wallert; Melanie Ziegler; Xiaowei Wang; Ana Maluenda; Xiaoqiu Xu; May Lin Yap; Roman Witt; Corey Giles; Stefan Kluge; Marcus Hortmann; Jianxiang Zhang; Peter Meikle; Stefan Lorkowski; Karlheinz Peter

16

The antioxidant and antiapoptotic effects of crocin pretreatment on global cerebral ischemia reperfusion injury induced by four vessels occlusion in rats

Life Sciences 154 (2016)

Serdar Oruc; Yücel Gönül; Kamil Tunay; Oya Akpinar Oruc; Mehmet Fatih Bozkurt; Ergün Karavelioğlu; Erman Bağcıoğlu; Kerem Senol Coşkun; Sefa Celik

17

Study of the cardioprotective effects of crocin on Human Cardiac Myocyte cells and reduction of oxidative stress produced by aluminum phosphide poisoning

Journal of Pharmacy and Pharmacology 73(11) (2021)

Mastoureh Naddafi; Mohammad Ali Eghbal; Mahmoud Ghazi-Khansari; Mohammad Reza Sattari; Yadollah Azarmi

18

Antiinflammatory, Antioxidant, and Immunomodulatory Effects ofCrocus sativusL. and its Main Constituents

Phytotherapy Research 30(7) (2016)

Mohammad Hossein Boskabady; Tahereh Farkhondeh

19

Ameliorative effects of crocin on paraquat-induced oxidative stress in testis of adult mice: An experimental study

International Journal of Reproductive BioMedicine (IJRM) 17(11) (2019)

Fahime Sadat Kamali; Rasoul Shahrooz; Golamreza Najafi; Mazdak Razi

20

Protective effects of crocin on testicular torsion/detorsion in rats

Theriogenology 173 (2021)

Vahid Ganjiani; Nasrollah Ahmadi; Mohammad Reza Divar; Hassan Sharifiyazdi; Abdolhamid Meimandi-Parizi

21

Platelet-rich plasma enhances remodeling of combined gastrocnemius muscle and Achilles tendon injuries in rat model: Reducing fibrosis, modulating gene (MMP9, Bax, HMGB1, and IGF) expression, and restoring histopathological and ultrastructural changes

Tissue and Cell 93 (2025)

Manal Mohammad Morsy; Basma Salah; Mohey E.E. Hulail; Walied Abdo; Hala Mahfouz; Zaki H. Hakami; Ahmad Alsulimani; Sulaiman Mohammed Alnasser; Alaa S. Alhegaili; Tarek kamal Abouzed; Ehab Kotb Elmahallawy; Mona A. Abdel-Kareem

22

Crocin Modulates AKT/mTORC1/ULK1 Cascade to Attenuate Ferritinophagy‐Induced Colonic Oxidative Injury in Ulcerative Colitis: Network Pharmacology, Molecular Docking, and Experimental Validation

Phytotherapy Research 40(5) (2026)

Mamdouh A. Oraby; Sherif S. Abdel Mageed; Mohammed S. Elballal; Amanallah El‐Bahrawy; Henwa M. Ibrahim; Menna M. Ayoub; Yasser M. Moustafa; Maram Mohammed El Tabaa; Manar Mohammed El Tabaa

25

An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin

Biomedicine & Pharmacotherapy 153 (2022)

Sepideh Bastani; Vahid Vahedian; Mohsen Rashidi; Amirabbas Mir; Sepideh Mirzaei; Iraj Alipourfard; Farhad Pouremamali; Hamidreza Nejabati; Jamileh kadkhoda; Nazila Fathi Maroufi; Maryam Akbarzadeh