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42 resultsUpdated October 25, 2026

α-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury

Redox Biology 26 (2019)

Maria Wallert; Melanie Ziegler; Xiaowei Wang; Ana C. Maluenda; Xiaoqiu Xu; May Lin Yap; Roman Witt; Corey Giles; Stefan Kluge; Marcus Hortmann; Jianxiang Zhang; Peter J. Meikle; Stefan Lorkowski A; Karlheinz Peter

Antiinflammatory, Antioxidant, and Immunomodulatory Effects ofCrocus sativusL. and its Main Constituents

Phytotherapy Research 30(7) (2016)

Mohammad Hossein Boskabady; Tahereh Farkhondeh

An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin

Biomedicine & Pharmacotherapy 153 (2022)

Sepideh Bastani; Vahid Vahedian; Mohsen Rashidi; Amirabbas Mir; Sepideh Mirzaei; Iraj Alipourfard; Farhad Pouremamali; Hamid Reza Nejabati; Jamileh Kadkhoda; Nazila Fathi Maroufi; Maryam Akbarzadeh

Crocin mediated amelioration of oxidative burden and inflammatory cascade suppresses diabetic nephropathy progression in diabetic rats

Chemico-Biological Interactions 284 (2018)

Hadeer O. Abou-Hany; Hoda Atef; Eman Said; Hassan A. El‐Kashef; Hatem A. Salem

Crocin protects cardiomyocytes against LPS-Induced inflammation

Pharmacological Reports 71(6) (2019)

Vafa Baradaran Rahimi; Mohammad Taghi Khammar; Hassan Rakhshandeh; Alireza Samzadeh‐Kermani; Azar Hosseini; Vahid Reza Askari

The Impact of Vitamin E Supplementation on Oxidative Stress, Cognitive Functions, and Aging‐Related Gene Expression in Aged Mice

Food Science & Nutrition 12(11) (2024)

Farnoosh Molavi Vasei; Mohammad Yasin Zamanian; Maryam Golmohammadi; Mehdi Mahmoodi; Morteza Khademalhosseini; Tayyebeh Tavakoli; Ozra Sadat Esmaeili; Sadegh Zarei; Mohammad Reza Mirzaei; Mohammad Reza Hajizadeh

Treatment with crocin improves cardiac dysfunction by normalizing autophagy and inhibiting apoptosis in STZ-induced diabetic cardiomyopathy

Nutrition Metabolism and Cardiovascular Diseases 28(9) (2018)

Konstantinos G. Feidantsis; Kyriakos Mellidis; Eleftheria Galatou; Z Sinakos; Antigone Lazou

Crocin modulates IL-4/IL-13 signaling and ameliorates experimentally induced allergic airway asthma in a murine model

International Immunopharmacology 50 (2017)

Haidy Yosri; Wagdi Fawzi Elkashef; Eman Said; Nariman M. Gameil

Crocin treatment prevents doxorubicin-induced cardiotoxicity in rats

Life Sciences 157 (2016)

Nasser Razmaraii; Hossein Babaei; Alireza Mohajjel Nayebi; Gholamreza Assadnassab; Javad Ashrafi Helan; Yadollah Azarmi

The antioxidant and antiapoptotic effects of crocin pretreatment on global cerebral ischemia reperfusion injury induced by four vessels occlusion in rats

Life Sciences 154 (2016)

Serdar Oruç; Yücel Gönül; Kamil Tünay; Oya Akpınar Oruç; Mehmet Fatih Bozkurt; Ergün Karavelioğlu; Erman Bağcıoğlu; Kerem Senol Coşkun; Sefa Celik

The Beneficial Effects of Saffron Extract on Potential Oxidative Stress in Cardiovascular Diseases

Oxidative Medicine and Cellular Longevity 2021(1) (2021)

Xin Su; Chao Yuan; Li Wang; Runqi Chen; Xiangying Li; Yijun Zhang; Can Liu; Xu Liu; Wanping Liang; Yanwei Xing

Crocin-Elicited Autophagy Rescues Myocardial Ischemia/Reperfusion Injury via Paradoxical Mechanisms

The American Journal of Chinese Medicine 44(03) (2016)

Chao Zeng; Hu Li; Zhiwen Fan; Lei Zhong; Zhen Guo; Yaping Guo; Yusheng Xi

Protective effects of crocin and zinc sulfate on hepatic ischemia-reperfusion injury in rats: a comparative experimental model study

Biomedicine & Pharmacotherapy 96 (2017)

Seyyed Ali Mard; Ghaidafeh Akbari; Mahin Dianat; Esrafil Mansouri

A comprehensive review on regulatory effects of crocin on ischemia/reperfusion injury in multiple organs

Biomedicine & Pharmacotherapy 99 (2018)

Ghaidafeh Akbari; Seyyed Ali Mard; Ali Veisi

Protective effects of crocin on testicular torsion/detorsion in rats

Theriogenology 173 (2021)

Vahid Ganjiani; Nasrollah Ahmadi; Mohammad Reza Divar; Hassan Sharifiyazdi; Abdolhamid Meimandi-Parizi

The effects of crocin, insulin and their co-administration on the heart function and pathology in streptozotocin-induced diabetic rats.

PubMed 6(6) (2016)

Amir Abbas Farshid; Esmaeal Tamaddonfard; Masoumeh Moradi-Arzeloo; Navideh Mirzakhani

The apocarotenoid production in microbial biofactories: An overview

Journal of Biotechnology 374 (2023)

Ressin Varghese; Tinamoni Buragohain; Ishani Banerjee; Rishyani Mukherjee; Shraddha Naresh Penshanwar; Swapna Agasti; Siva Ramamoorthy

Crocin Modulates AKT / mTORC1 / ULK1 Cascade to Attenuate Ferritinophagy‐Induced Colonic Oxidative Injury in Ulcerative Colitis: Network Pharmacology, Molecular Docking, and Experimental Validation

Phytotherapy Research 40(5) (2026)

Mamdouh A. Oraby; Sherif S. Abdel Mageed; Mohammed Salah Elballal; Amanallah El-Bahrawy; Henwa M. Ibrahim; Menna M. Ayoub; Yasser M. Moustafa; Maram Mohammed El Tabaa; Maram Mohammed El Tabaa; Manar Mohammed El Tabaa; Manar Mohammed El Tabaa

Crocin mitigates carbon tetrachloride-induced liver toxicity in rats

Journal of Taibah University Medical Sciences 10(2) (2014)

Saleh Bahashwan; Memy H. Hassan; Hamdy A.A. Aly; Mohamed Ghobara; Hesham Abdelaziz El-Beshbishy; Ibrahim Busati

Moderating effects of crocin on some stress oxidative markers in rat brain following demyelination with ethidium bromide

Heliyon 5(2) (2019)

Hadi Fathimoghadam; Yaghoub Farbod; Ata Ghadiri; Rouholah Fatemi

Crocin Abrogates Carbon Tetrachloride-Induced Renal Toxicity in Rats via Modulation of Metabolizing Enzymes and Diminution of Oxidative Stress, Apoptosis, and Inflammatory Cytokines

Journal of Biochemical and Molecular Toxicology 29(7) (2015)

Memy H. Hassan; Saleh A. Bahashawan; Tamer M. Abdelghany; Gamil M. Abd‐Allah; Mohamed Ghobara

Picroside II inhibits hypoxia/reoxygenation-induced cardiomyocyte apoptosis by ameliorating mitochondrial function through a mechanism involving a decrease in reactive oxygen species production

International Journal of Molecular Medicine 35(2) (2014)

JIAN-ZHE LI; Shuyi Yu; DAN MO; Xiuneng Tang; QING-RUI SHAO

Crocin attenuates oxidative stress and inflammation in myocardial infarction induced by isoprenaline via PPARγ activation in diabetic rats

Journal of Diabetes & Metabolic Disorders 19(2) (2020)

Mohammad Badavi; Seyyed Ali Mard; Mahin Dianat; Neda Dashtbozorgi

The effects of prenatal androgen exposure on cardiac function and tolerance to ischemia/reperfusion injury in male and female rats during adulthood

Life Sciences 229 (2019)

Mahsa Noroozzadeh; Mohammad Reza Raoufy; Razieh Bidhendi Yarandi; Farzaneh Faraji Shahrivar; Fahimeh Ramezani Tehrani

Analysis of Anti-Arrhythmic Impacts of Crocin through Estimation of Expression of Cx43 in Myocardial Infarction Using a Rat Animal Model

ACS Omega 7(42) (2022)

Huan Li; Jian Li; Juanli Wang; Obaid Afzal; Abdulmalik Saleh Alfawaz Altamimi; Shehla Nasar Mir Najib Ullah; Sireen Abdul Rahim Shilbayeh; Alnada Abdalla Mohamed Ibrahim; Shahanavaj Khan

Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10.

PubMed 25(4) (2022)

Esmat Radmanesh; Mahin Dianat; Mohammad Badavi; Gholamreza Goudarzi; Seyyed Ali Mard; Maryam Radan

The Protective Effect of Melatonin vs. Vitamin E in the Ischemic/Reperfused Skeletal Muscle in the Adult Male Rat Model

Journal of Cytology & Histology s3 (2015)

Enas Ali Kamel Mohamed

Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart.

PubMed 27(7) (2024)

Narges Atefipour; Mahin Dianat; Mohammad Badavi; Maryam Radan; Seyyed Ali Mard

Ameliorative effects of crocin on paraquat-induced oxidative stress in testis of adult mice: An experimental study

International Journal of Reproductive BioMedicine (IJRM) 17(11) (2019)

Fahime Sadat Kamali; Rasoul Shahrooz; Golamreza Najafi; Mazdak Razi

Effect of crocin on cardiac antioxidants, and hemodynamic parameters after injuries induced by hepatic ischemia-reperfusion in rats.

PubMed 22(3) (2019)

Ghaidafeh Akbari; Seyyed Ali Mard; Mahin Dianat

Study of the cardioprotective effects of crocin on Human Cardiac Myocyte cells and reduction of oxidative stress produced by aluminum phosphide poisoning

Journal of Pharmacy and Pharmacology 73(11) (2021)

Mastoureh Naddafi; Mohammad Ali Eghbal; Mahmoud Ghazi‐Khansari; Mohammad Reza Sattari; Yadollah Azarmi

Exogenous apelin changes alpha and beta myosin heavy chain mRNA expression and improves cardiac function in PTU-induced hypothyroid rats

Gene 595(1) (2016)

Farzaneh Faraji Shahrivar; Mohammad Badavi; Mahin Dianat; Seyyed Ali Mard; Akram Ahangarpour; Alireza Samarbafzadeh

Evaluation of possible effects of crocin against nitrate tolerance and endothelial dysfunction.

PubMed 23(3) (2020)

Seyedeh Farzaneh Omidkhoda; Bibi Marjan Razavi; Mohsen Imenshahidi; Maryam Rameshrad; Hossein Hosseinzadeh

Carotenoids and Vitamins of Pollen

Springer eBooks (2023)

Rodica Mărgăoan; Mihaiela Cornea‐Cipcigan

Platelet-rich plasma enhances remodeling of combined gastrocnemius muscle and Achilles tendon injuries in rat model: Reducing fibrosis, modulating gene (MMP9, Bax, HMGB1, and IGF) expression, and restoring histopathological and ultrastructural changes

Tissue and Cell 93 (2024)

Manal Mohammad Morsy; Basma Salah; Mohey A. E. Hulail; Walied Abdo; Hala Mahfouz; Zaki H. Hakami; Ahmad Alsulimani; Sulaiman Mohammed Alnasser; Alaa S. Alhegaili; Tarek Kamal Abouzed; Ehab Kotb Elmahallawy; Mona A. Abdel‐Kareem

Cardiac function and tolerance to ischemia/reperfusion injury in a rat model of polycystic ovary syndrome during the postmenopausal period

Life Sciences 262 (2020)

Mahsa Noroozzadeh; Mohammad Reza Raoufy; Razieh Bidhendi Yarandi; Farzaneh Faraji Shahrivar; Naghmeh Moghimi; Fahimeh Ramezani Tehrani

The Possible Protective Role of Crocin and Pumpkin Seed Oil against Lead-Induced Testicular Cytotoxicity in Adult Male Albino Rat.Hormonal, Histological and Immunohistochemical study.

Benha Medical Journal 0(0) (2022)

Hend Ragab Mousa; Amany M. Allam; Ali Ali Mohamed

Effect of fetal hyperexposure to testosterone on cardiac tolerance to ischemia-reperfusion injury in male rats in adulthood

Scientific Journal of Kurdistan University of Medical Sciences 27(1) (2022)

Mahsa Noroozzadeh; Nahid Sarahian; Razieh Bidhendi Yarandi; Fahimeh Ramezani Tehrani