Effects of adding dexmedetomidine to lidocaine on the onset and duration of axillary block for upper extremity surgeries

Behrooz Zaman; Samad  Noorizad; Seyed Alireza Seyed Siamdoust; Seyed Hassan Etemadi; Sina Askarian  Omran; Mahzad Alimian

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Effects of adding dexmedetomidine to lidocaine on the onset and duration of axillary block for upper extremity surgeries

Author(s):

Behrooz Zaman¹,

Samad Noorizad¹,

Seyed Alireza Seyed Siamdoust¹,

Seyed Hassan Etemadi¹,

Sina Askarian Omran²,

Mahzad Alimian^1,*

1Dept. of Anesthesiology and Regional Anesthesia, Iran University of Medical Sciences, Tehran, Iran

2Anesthesiologist, Aja Hospital, Hormozgan, Iran

Journal of Kermanshah University of Medical Sciences:Vol. 21, issue 3; e69237

Published online:Dec 30, 2017

Article type:Research Article

Received:Aug 12, 2017

Accepted:Nov 07, 2017

How to Cite:Zaman B, Noorizad S, Seyed Siamdoust SA, Etemadi SH, Askarian Omran S, et al. Effects of adding dexmedetomidine to lidocaine on the onset and duration of axillary block for upper extremity surgeries. J Kermanshah Univ Med Sci. 2017;21(3):e69237. doi:

Abstract

Introduction: Dexmedetomidine, which is an alpha 2 agonist, reduces the transmission of pain signals and has an independent inhibitory effect on nerve action potential. The purpose of this study was to examine the effects of adding dexmedetomidine to lidocaine in an axillary block.

Methods: In this randomized, double-blind study 40 patients included patients were divided randomly into two groups of 20: In the first group, 39 cc of 1% lidocaine plus 1cc of normal saline was administered and the 2^nd group received dexmedetomidine 1cc (100µg) in addition to 39 cc of 1% lidocaine. The onset and persistence of the sensorimotor block and hemodynamic changes including heart rate and systolic and diastolic blood pressure before, during, and after surgery were compared.

Results: Age, sex, type of surgery, duration of surgery, and other demographic characteristics were not significantly different in two groups (P>0.05). Onset of the sensory and motor block was similar in both groups, but the persistence of the sensory and motor block and analgesia in the treatment group was significantly higher (P<0.05). The VAS score was lower in cases than controls. Hemodynamic change differences between the two groups were statistically significant (P<0.05).

Conclusion: The results of this study showed that adding dexmedetomidine to lidocaine in an axillary block did not alter the onset of the sensory and motor block, but the sensory and motor block duration and analgesia was increased. Despite significant differences in hemodynamic responses between the two groups, these changes were not clinically significant in ASA1 patients.

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References

The Effect of Ketamine and Dexamethasone in Combination with Lidocaine on the Onset and Duration of Axillary Block in Hand and Forearm Soft Tissue Surgery

Behrooz Zaman,

Siavash Hojjati Ashrafi,

Seyedalireza Seyed Siamdoust,

Valiollah Hassani,

Siavash Mohamad Taheri,

Samad Noorizad

Zaman B, Hojjati Ashrafi S, Seyed Siamdoust S, Hassani V, Mohamad Taheri S, et al. The Effect of Ketamine and Dexamethasone in Combination with Lidocaine on the Onset and Duration of Axillary Block in Hand and Forearm Soft Tissue Surgery. Anesth Pain Med. 2017;7(5):e15570. doi: https://doi.org/10.5812/aapm.15570

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May

2021

A Comparative Study of Clonidine and Dexmedetomidine with 0.5% Levobupivacaine in ultrasound-guided Axillary Brachial Plexus Block for Upper Limb Surgeries

Valluri Anil Kumar,

prithviraj,

S Md Shamiq Muthaib

Kumar VA, P, Shamiq Muthaib SM. A Comparative Study of Clonidine and Dexmedetomidine with 0.5% Levobupivacaine in ultrasound-guided Axillary Brachial Plexus Block for Upper Limb Surgeries. J Cell Mol Anesth. 2021;6(3):e150254. doi: https://doi.org/10.22037/jcma.v6i3.34421

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Jul

2018

The Effect of Adding Dexmedetomidine as an Adjuvant to Lidocaine in Forearm Fracture Surgeries by Supraclavicular Block Procedure Under Ultrasound-Guided

Reza Akhondzadeh,

Mahbobe Rashidi,

Mohammadreza Gousheh,

Alireza Olapour,

Amirhossein Baniahmad

Akhondzadeh R, Rashidi M, Gousheh M, Olapour A, Baniahmad A. The Effect of Adding Dexmedetomidine as an Adjuvant to Lidocaine in Forearm Fracture Surgeries by Supraclavicular Block Procedure Under Ultrasound-Guided. Anesth Pain Med. 2018;8(4):e74355. doi: https://doi.org/10.5812/aapm.74355

27

Aug

2019

Comparison of Dexmedetomidine and Morphine as Adjuvants to Bupivacaine for Epidural Anesthesia in Leg Fracture Surgery: A Randomized Clinical Trial

Mohammadreza Gousheh,

Reza Akhondzadeh,

Mahbobe Rashidi,

Alireza Olapour,

Fatemeh Moftakhar

Gousheh M, Akhondzadeh R, Rashidi M, Olapour A, Moftakhar F. Comparison of Dexmedetomidine and Morphine as Adjuvants to Bupivacaine for Epidural Anesthesia in Leg Fracture Surgery: A Randomized Clinical Trial. Anesth Pain Med. 2019;9(4):e91480. doi: https://doi.org/10.5812/aapm.91480

28

Jun

2020

Randomized Control Trial Using Ropivacaine in Spinal Anaesthesia With and Without Intravenous Dexmedetomidine in Lower Limb Surgeries

Abhishek MS

MS A. Randomized Control Trial Using Ropivacaine in Spinal Anaesthesia With and Without Intravenous Dexmedetomidine in Lower Limb Surgeries. J Cell Mol Anesth. 2020;5(3):e149631. doi: https://doi.org/10.22037/jcma.v5i3.30971

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Author(s):

Behrooz Zaman:[PubMed][Scholar]
Samad Noorizad:[PubMed][Scholar]
Seyed Alireza Seyed Siamdoust:[PubMed][Scholar]
Seyed Hassan Etemadi:[PubMed][Scholar]
Sina Askarian Omran:[PubMed][Scholar]
Mahzad Alimian:[PubMed][Scholar]

Peer-reviewed Medical Quarterly

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Effects of adding dexmedetomidine to lidocaine on the onset and duration of axillary block for upper extremity surgeries

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