Cover image of the article: The effect of adding epinephrine to combination of sufentanil and bupivacaine in spinal analgesia during labor

Image Credit:J Kermanshah Univ Med Sci

The effect of adding epinephrine to combination of sufentanil and bupivacaine in spinal analgesia during labor

Authors

Parisa Golfam1,*, Ali Karbasforoushan1, Ali Asghar Keshazar2, Mahmoud Fakhri3
1Dept. of Anesthesiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
2Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Andorra
3Dept. of Nursing, School of Nursing and Midweifary, Kermanshah University of Medical Sciences, Kermanshah, Iran
*Corresponding Author: Corresponding author: Parisa Golfam, Dept. of Anesthesiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran, Tel: +98 831 4276302 Email: Pargolfam@yahoo.com

Journal of Kermanshah University of Medical Sciences:Vol. 15, issue 1; e69714
Published online:May 19, 2011
Article type:Research Article
Received:Dec 27, 2009
Accepted:May 25, 2010
How to Cite:Golfam P, Karbasforoushan A, Keshazar AA, Fakhri M. The effect of adding epinephrine to combination of sufentanil and bupivacaine in spinal analgesia during labor. J Kermanshah Univ Med Sci. 2011;15(1):e69714. doi:

Abstract

Background: Spinal analgesia is one of the effective and rapid methods for labor. It is not commonly used because of short duration of analgesia and motor block, which limits mother's force in labor progression. We attempted to prolong duration and quality of analgesia by adding Epinephrine.

Methods: In this quasi-experimental study 90 pregnant women gravid II and III who referred to Motazedi and Imam Reza Educational & Medical Centers were recruited and divided into two groups of case and control (45 subjects in each group). The case group received spinal analgesia using Sufentanil and Bupivacaine, and Epinephrine while the control group received Sufentanil and Bupivacaine. Data including feeling of pain, motor block, duration of analgesia, fetal heart rate, nausea and vomiting, blood pressure was collected and analyzed using chi-square and t test.  

Results: duration of analgesia and vomiting were significantly increased in the case group. (p=0.001, p=0.01 respectively). Hemodynamic status in mothers and Apgar score of neonates were not significantly different between two groups.

Conclusion: It seems that adding Epinephrine to Sufentanil and Bupivacaine could increase analgesia duration without altering in sensory level although could increase nausea and vomiting its recommended in labor analgesia.

Highlights

Fulltext

The full text of this article is available on PDF.

References

  • 1.
    The references of this article is available on PDF.

Copyright

© 2011, Journal of Kermanshah University of Medical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.

Similar Articles

15
Oct
2018
Comparison of Adding Sufentanil and Low-Dose Epinephrine to Bupivacaine in Spinal Anesthesia: A Randomized, Double-Blind, Clinical Trial

Comparison of Adding Sufentanil and Low-Dose Epinephrine to Bupivacaine in Spinal Anesthesia: A Randomized, Double-Blind, Clinical Trial

Pooya Derakhshan,
Farnad Imani,
Zahra Sadat Koleini,
Amin Barati

Derakhshan P, Imani F, Koleini ZS, Barati A. Comparison of Adding Sufentanil and Low-Dose Epinephrine to Bupivacaine in Spinal Anesthesia: A Randomized, Double-Blind, Clinical Trial. Anesth Pain Med. 2018;8(5):e69600. doi: https://doi.org/10.5812/aapm.69600

7
Feb
2014
Addition of Intrathecal Fentanyl or Meperidine to Lidocaine and Epinephrine for Spinal Anesthesia in Elective Cesarean Delivery

Addition of Intrathecal Fentanyl or Meperidine to Lidocaine and Epinephrine for Spinal Anesthesia in Elective Cesarean Delivery

Farnoush Farzi,
Ali Mirmansouri,
Kambiz Forghanparast,
Abtin Heydarzadeh,
Mehrsima Abdollahzadeh,
Fatemeh Jahanyar Moghadam

Farzi F, Mirmansouri A, Forghanparast K, Heydarzadeh A, Abdollahzadeh M, et al. Addition of Intrathecal Fentanyl or Meperidine to Lidocaine and Epinephrine for Spinal Anesthesia in Elective Cesarean Delivery. Anesth Pain Med. 2014;4(1):e14081. doi: https://doi.org/10.5812/aapm.14081

26
Jul
2023
Post-cesarean Delivery Analgesia Using Spinal Anesthesia: Ropivacaine-Fentanyl vs. Ropivacaine-Sufentanil

Post-cesarean Delivery Analgesia Using Spinal Anesthesia: Ropivacaine-Fentanyl vs. Ropivacaine-Sufentanil

Ahmad Reza Mohtadi,
Atusa Ahmadi Chegeni,
Kaveh Behaeen,
Mohsen Savaie,
Ali Ghomeishi

Mohtadi AR, Ahmadi Chegeni A, Behaeen K, Savaie M, Ghomeishi A. Post-cesarean Delivery Analgesia Using Spinal Anesthesia: Ropivacaine-Fentanyl vs. Ropivacaine-Sufentanil. Anesth Pain Med. 2023;13(4):e138067. doi: https://doi.org/10.5812/aapm-138067

27
Aug
2017
Comparing the Effect of Adding Fentanyl, Sufentanil, and Placebo with Intrathecal Bupivacaine on Duration of Analgesia and Complications of Spinal Anesthesia in Patients Undergoing Cesarean Section

Comparing the Effect of Adding Fentanyl, Sufentanil, and Placebo with Intrathecal Bupivacaine on Duration of Analgesia and Complications of Spinal Anesthesia in Patients Undergoing Cesarean Section

Farnoush Farzi,
Ali Mirmansouri,
Bahram Naderi Nabi,
Zahra Atrkar Roushan,
Samaneh Ghazanfar Tehran,
Mona Nematollahi Sani
,et al.

Farzi F, Mirmansouri A, Naderi Nabi B, Atrkar Roushan Z, Ghazanfar Tehran S, et al. Comparing the Effect of Adding Fentanyl, Sufentanil, and Placebo with Intrathecal Bupivacaine on Duration of Analgesia and Complications of Spinal Anesthesia in Patients Undergoing Cesarean Section. Anesth Pain Med. 2017;7(5):e12738. doi: https://doi.org/10.5812/aapm.12738

15
Nov
2012
The Comparison of Pain Relief between Postoperative Wound Infiltration with Bupivacaine 0.5% Combined with Epinephrine after Elective Cesarean Section

The Comparison of Pain Relief between Postoperative Wound Infiltration with Bupivacaine 0.5% Combined with Epinephrine after Elective Cesarean Section

vida modarres nejad,
batool Motamedi,
Mazyar Nafisy

modarres nejad V, Motamedi B, Nafisy M. The Comparison of Pain Relief between Postoperative Wound Infiltration with Bupivacaine 0.5% Combined with Epinephrine after Elective Cesarean Section. Zahedan J Res Med Sci. 2013;15(4):e92997. doi:

More by these authors

Parisa GolfamPubMedScholar
Ali KarbasforoushanPubMedScholar
Ali Asghar KeshazarPubMedScholar
Mahmoud FakhriPubMedScholar
Share
Cited by
Metrics