The antibacterial properties of methanolic extract of Teucrium polium against MRSA

How to Cite:Motamedi H, Aalivand S, Ebrahimian M, Moosavian SM. The antibacterial properties of methanolic extract of Teucrium polium against MRSA. J Kermanshah Univ Med Sci. 2015;18(10):e74003. doi: https://doi.org/10.22110/jkums.v18i10.2039

Abstract

Background: Infections due to resistant Staphylococcus aureus strains are progressively increased annually. So, finding new antibiotic resources is of great importance. Medicinal plants as a natural source of antibiotics are considered a good option. Teucrium polium, a native plant in Khouzestan, has been used for a long time in folk medicine. The aim of the present study was to investigate the antibacterial potential of this plant against methicillin resistant S. aureus (MRSA) strains.

Methods: Methanolic extract was prepared from the flowers of T. polium, and its antibacterial activity was evaluated against 50 MRSA isolates by Kirby-Bauer disc diffusion method. These isolates were also screened for mec and pvl genes.

Results: From 50 isolates, 20 isolates were selected and subjected to antibacterial analysis. From these, 14 isolates were positive for mecA gene, 2 of them were positive for pvl gene and 4 of them didn't have mec or pvl genes. None of MRSA isolates were positive for both genes. The results showed that the methanolic extract of T. polium has considerable inhibitory effect against MRSA, even at the lowest concentration. mecA and pvl negative strains were more sensitive to methanolic extract, but the presence of mecA didn not have any significant effect on their resistance.

Conclusion: Based on these findings and with regard to the increasing trend in hospital-acquired S. aureus infections, it can be suggested that T.polium is an effective medicinal plant for treatment of infections caused by this bacterium and can be used as a natural source to produce new antibiotics.

Keywords

Fulltext

References

1.
The references of this article is available on PDF.

Antibacterial Effect of Teucrium polium on the Bacteria Causing Urinary Tract Infections

Samira Shahba,

Mohammad Bokaeian,

Nour Amir Mozafari-Sabet,

Ali Saeidpour-Pariz,

Zakaria Bamer,

Mohammad Nikbin

Shahba S, Bokaeian M, Mozafari-Sabet NA, Saeidpour-Pariz A, Bamer Z, et al. Antibacterial Effect of Teucrium polium on the Bacteria Causing Urinary Tract Infections. Zahedan J Res Med Sci. 2014;16(3):. doi:

2

Aug

2022

Investigation of Antioxidant, Antifungal, Antibacterial, and Anti-inflammatory Effects of Teucrium polium on Common Pathogens in Vaginitis: A Review

Tayebeh Ilaghinezhad Bardsiri,

Somaye Moayedi,

Razieh Nabi Meybodi,

Mohammad Torbati,

Tayebeh Mokhtari Sorkhani

Ilaghinezhad Bardsiri T, Moayedi S, Nabi Meybodi R, Torbati M, Mokhtari Sorkhani T. Investigation of Antioxidant, Antifungal, Antibacterial, and Anti-inflammatory Effects of Teucrium polium on Common Pathogens in Vaginitis: A Review. Jundishapur J Nat Pharm Prod. 2022;17(4):e128060. doi: https://doi.org/10.5812/jjnpp-128060

26

Sep

2020

Jundishapur Journal of Natural Pharmaceutical Products

Anti-Mutagenicity and Apoptotic Effects of Teucrium polium L. Essential Oil in HT29 Cell Line

Fataneh Hashem-Dabaghian,

Asie Shojaii,

Jinous Asgarpanah,

Maliheh Entezari

Hashem-Dabaghian F, Shojaii A, Asgarpanah J, Entezari M. Anti-Mutagenicity and Apoptotic Effects of Teucrium polium L. Essential Oil in HT29 Cell Line. Jundishapur J Nat Pharm Prod. 2020;15(3):e79559. doi: https://doi.org/10.5812/jjnpp.79559

31

Oct

2010

Anticonvulsant Activity of Teucrium polium Against Seizure Induced by PTZ and MES in Mice

Mohammad Javad Khoshnood-Mansoorkhani,

Mahmood Reza Moein,

Narjes Oveisi

Khoshnood-Mansoorkhani MJ, Moein MR, Oveisi N. Anticonvulsant Activity of Teucrium polium Against Seizure Induced by PTZ and MES in Mice. Iran J Pharm Res. 2010;9(4):e126076. doi: https://doi.org/10.22037/ijpr.2010.905

9

Apr

2016

Investigating the Antibacterial Effects of Plant Extracts on Pseudomonas aeruginosa and Escherichia coli

Somayeh Jahani,

Saeide Saeidi,

Fereshteh Javadian,

Zahra Akbarizadeh,

Ali Sobhanizade

Jahani S, Saeidi S, Javadian F, Akbarizadeh Z, Sobhanizade A. Investigating the Antibacterial Effects of Plant Extracts on Pseudomonas aeruginosa and Escherichia coli. Int J Infect. 2016;3(2):e34081. doi: https://doi.org/10.17795/iji-34081

Import into EndNote Import into BibTex

Crossmark

Checking

Share on

Comments

Number of Comments:0

Cited by

Scopus by DOI: 0
Last Update: 1 month ago
Scopus by Title: 0
Last Update: 1 month ago
Scopus by Title (Ref): 7
Last Update: 1 month ago
CrossRef: 0
Last Update: 4 days ago

Metrics

Licensing and reuse information

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC

Search Relations

Author(s):

Hossein Motamedi:[PubMed][Scholar]
Shole Aalivand:[PubMed][Scholar]
Maryam Ebrahimian:[PubMed][Scholar]
Seyyed Mojtaba Moosavian:[PubMed][Scholar]

Peer-reviewed Medical Quarterly

Outlines

The antibacterial properties of methanolic extract of Teucrium polium against MRSA

Abstract

Fulltext

References

Similar Articles

Antibacterial Effect of Teucrium polium on the Bacteria Causing Urinary Tract Infections

Investigation of Antioxidant, Antifungal, Antibacterial, and Anti-inflammatory Effects of Teucrium polium on Common Pathogens in Vaginitis: A Review

Anti-Mutagenicity and Apoptotic Effects of Teucrium polium L. Essential Oil in HT29 Cell Line

Anticonvulsant Activity of Teucrium polium Against Seizure Induced by PTZ and MES in Mice

Investigating the Antibacterial Effects of Plant Extracts on Pseudomonas aeruginosa and Escherichia coli

Crossmark

Checking

Last Update: 1 month ago

Last Update: 1 month ago

Last Update: 1 month ago

Last Update: 4 days ago