Journal of Kermanshah University of Medical Sciences
Peer-reviewed Medical Quarterly
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Association between HbA1C value at the time of diagnosis and response rate to treatment in children with type I diabetes mellitus
Author(s):
1Dept. of Pediatrics, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
2Dept. of Biostatistics and Epidemiology, Social Development and Health Promotion Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
*Corresponding Author: Corresponding author: Mastooreh Hosseini, Dept. of Pediatrics, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran, Tel: +988337223390 Email: [email protected]
Published online:Sep 29, 2014
Article type:Research Article
Received:Apr 19, 2014
Accepted:Sep 16, 2014
How to Cite:Gheini S, Hosseini M, Rezaei M. Association between HbA1C value at the time of diagnosis and response rate to treatment in children with type I diabetes mellitus. J Kermanshah Univ Med Sci. 2014;18(6):e74084. doi: https://doi.org/10.22110/jkums.v18i6.1671
Abstract
Background: HbA1C has been used as an important factor for assessment of blood glucose control in diabetic patients during the past few months. The aim of this study was to use HbA1c at the time of diagnosis in diabetic children as a predictive factor to control diabetes in the following months.
Methods: In this analytic -comparative study, HbA1C was analyzed in 60 patients with diabetes type 1 at the time of diagnosis and then rechecked 6 months after insulin treatment. The results were evaluated in terms of analysis of HbA1c by U-Mann-Whitney test and analysis of predictive value of HbA1c by Roc curve.
Results: The findings revealed that at the time of diagnosis, 47 diabetic infants were reported with HbA1C≤8 and 8 cases with HbA1C≥10. After starting the treatment and finishing the 6-month period, 39 cases had HbA1C≤8 (P<0.05). Those with a lower level of HbA1C at the time of diagnosis indicated a better blood glucose control after 6 months of treatment.
Conclusion: The results showed lower level of HbA1C at the time of diagnosis is accompanied by a better blood glucose control after 6 months of treatment. Therefore, low level of HbA1c at the beginning of diabetes could be indicative of the level of glycemic control in the future.
References
- 1.The references of this article is available on PDF.
Copyright
© 2014, Journal of Kermanshah University of Medical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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