Journal of Kermanshah University of Medical Sciences
Peer-reviewed Medical Quarterly
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Evaluation of Valerians’ effect on sleep quantity and quality of menopausal women: cross-over clinical trial
Author(s):
Mandana Mirmohammadali1, Tahereh Zendehdel-Rakhshandeh1,*, Khosro Sadeghniyat-Haghighi2, Soghrat Faghihzadeh3, Mahshid Taheri41Dept. of Reproductive Health, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
2Occupational Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran
3Dept. of Biostatistics, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
4Nursing and Midwifery Care Research Center, Tehran University of Medical Sciences, Tehran, Iran
*Corresponding Author: Corresponding author: Tahereh Zendehdel-Rakhshandeh, Dept. of Reproductive Health, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran, Tel: +989124795212 Email: [email protected]
Published online:Feb 27, 2014
Article type:Research Article
Received:Aug 12, 2013
Accepted:Dec 10, 2013
How to Cite:Mirmohammadali M, Zendehdel-Rakhshandeh T, Sadeghniyat-Haghighi K, Faghihzadeh S, Taheri M. Evaluation of Valerians’ effect on sleep quantity and quality of menopausal women: cross-over clinical trial. J Kermanshah Univ Med Sci. 2014;17(11):e74306. doi: https://doi.org/10.22110/jkums.v17i11.1355
Abstract
Background: Menopause causes poor sleep quality in women, so that great throngs of menopausal women experience menopause-induced sleep disorders. This study was conducted to determine the effects of valerian extract on sleep quantity and quality of postmenopausal women.
Methods: This triple-blind, randomized, cross-over clinical trial was performed on 144 eligible postmenopausal women. Participants were randomly classified into two groups to use either 700 mg valerian extract (group A) or a placebo (group B) for one month. After a 2-week washout period, the treatment regimens were reversed. Sleep quantity and quality were evaluated using Pittsburgh and Insomnia Severity Index (ISI) questionnaires at baseline and after both phases of intervention.
Results: Mean score of Pittsburgh scale was 10.9±3.6 at baseline. Valerian reduced this score to 7.8±3.4 and 7.4±3 at the first and the second phase of intervention, respectively (P<0.001). After the first phase of intervention, ISI score was reduced to 2.87±0.62 in group A (P<0.001). It was reduced to 4.02±0.5 in group B after the second phase of intervention (P<0.001).
Conclusion: Daily consumption of 700 mg valerian improved sleep quantity and quality in postmenopausal women
References
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Copyright
© 2014, Journal of Kermanshah University of Medical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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