Cover image of the article: Chemical Composition and General Toxicity of Essential Oil Extracted from the Stalks and Flowers of Rheum Ribes L. Growing in Iran

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Chemical Composition and General Toxicity of Essential Oil Extracted from the Stalks and Flowers of Rheum Ribes L. Growing in Iran

Authors

Mohammad Reza Nikbakht1, Solmaz Esnaashari2, Fariba Heshmati Afshar3,*
1Novel Drug Delivery Research Center, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, I.R. Iran
2Drug Applied Research Centre, Tabriz University of Medical Sciences, Tabriz, I.R. Iran
3Medical Philosophy and History Research Center and Faculty of Traditional Medicine, Tabriz University of Medical Sciences, Tabriz, I.R. Iran
*Corresponding Author: Corresponding author: Medical Philosophy and History Research Center and Faculty of Traditional Medicine, Tabriz University of Medical Sciences, Tabriz, I.R. Iran. Email:heshmatif@live.com

Journal of Reports in Pharmaceutical Sciences:Vol. 2, issue 2; 165-170
Published online:Nov 12, 2013
Article type:Research Article
Received:Oct 14, 2013
Accepted:Nov 09, 2013
How to Cite:Nikbakht MR, Esnaashari S, Heshmati Afshar F. Chemical Composition and General Toxicity of Essential Oil Extracted from the Stalks and Flowers of Rheum Ribes L. Growing in Iran. J Rep Pharm Sci. 2013;2(2):e147750. doi:

Abstract

The essential oil of Rheum ribes L. stalks and flowers, growing in Iran, were extracted with hydro-distillation and analyzed by GC-MS. Thirty constituents representing 93.84% of Rheum oil were identified. The oil was found to be rich in hydrocarbons especially long-chain n-alkanes (80.81%). The most abundant components in the oil included tricosane (26.29%), heneicosane (26.07%), pentacosane (10.63%), heptacosane (10.37%) and palmitic acid (3.64%). The essential oil was also evaluated for general toxicity bioassay using brine shrimp lethality method. The toxicity profile of the oil indicated some degree of toxicity in comparison with podophyllotoxin. 

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Copyright

© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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