Osteogenesis effect of ginger (Zingiber officinale) hydroalcoholic extract in mouse embryos

Author(s):
Cambyz IrajieCambyz Irajie, Abdolrahim Ansari ShiriAbdolrahim Ansari Shiri, Parvin GhaemmaghamiParvin GhaemmaghamiParvin Ghaemmaghami ORCID, Farzaneh  DehghaniFarzaneh Dehghani, Tahereh Talaei-KhozaniTahereh Talaei-Khozani, Akram JamshidzadehAkram Jamshidzadeh, Romina TanidehRomina Tanideh, Elaham ZarenezhadElaham Zarenezhad, N. TanidehN. Tanideh,*, Aida IrajiAida Iraji

Koomesh:Vol. 24, issue 5; 691-698
Published online:Dec 02, 2022
Article type:Research Article
Received:Jun 01, 2021
Accepted:Apr 02, 2022
How to Cite:Irajie C, Ansari Shiri A, Ghaemmaghami P, Dehghani F, Talaei-Khozani T, et al. Osteogenesis effect of ginger (Zingiber officinale) hydroalcoholic extract in mouse embryos. koomesh. 2022;24(5):e152780. doi:

Abstract

References

  • 1.
    Poorrostami A, Farokhi F, Heidari R. Effect of hydroalcoholic extract of ginger on the liver of epileptic female rats treated with lamotrigine. Avicenna J Phytomed 2014; 4: 276.
  • 2.
    Dutta, S.; Mahalanobish, S.; Saha, S.; Ghosh, S.Sil, P. C. Natural products: An upcoming therapeutic approach to cancer. Food and Chemical Toxicology 2019,128, 240-55.
  • 3.
    Makpol S, Abdul Sani NF, Hakimi NH, Ab Rani N, Zakaria SN, Abd Rasid AF, et al. Zingiber officinale roscoe prevents DNA damage and improves muscle performance and bone integrity in old sprague dawley rats. Evid Bas Complement Altern Med 2020; 2020.##https://doi.org/10.1155/2020/3823780.
  • 4.
    White B. Ginger: an overview. Am Fam Phys 2007; 75: 1689-1691.##.
  • 5.
    Therkleson T. Ginger and osteoarthritis. 2012.
  • 6.
    gingerol in cancer: A comprehensive review. Phytother Res 2018; 32: 1885-1907.
  • 7.
    Nikkhah Bodagh M, Maleki I, Hekmatdoost A. Ginger in gastrointestinal disorders: a systematic review of clinical trials. Food Sci Nutr 2019; 7: 96-108.
  • 8.
    Banihani SA. Ginger and testosterone. Biomolecules 2018; 8: 119.
  • 9.
    Kumara M, Shylajab M, Nazeemc P, Babu T. 6-Gingerol is the most potent anticancerous compound in ginger (Zingiber officinale Rosc.). J Dev Drugs 2017; 6.
  • 10.
    Szen T, zk L, Baaran N. An overview and management of osteoporosis. Eur J Rheumatol 2017; 4: 46.
  • 11.
    Prior J. Progesterone for the prevention and treatment of osteoporosis in women. Climacteric 2018; 21: 366-374.
  • 12.
    Al-Muraikhi H, Chehab MA, Said H, Selim N. Assessing health beliefs about osteoporosis among women attending primary health care centres in Qatar. J Taibah Univ Med Sci 2017; 12: 349-355.
  • 13.
    Jabarpour E. Abedini A, Keshtkar A. Osteoporosis risk prediction using data mining algorithms. J Commun Health Res 2020; 9: 69-80.##https://doi.org/10.18502/jchr.v9i2.3401.
  • 14.
    Cohen A, KamandaKosseh M, Dempster DW, Zhou H, Mller R, Goff E, et al. Women with pregnancy and lactation-associated osteoporosis (PLO) have low bone remodeling rates at the tissue level. J Bone Miner Res 2019; 34: 1552-1561.
  • 15.
    Leere JS, Vestergaard P. Calcium metabolic disorders in pregnancy: Primary hyperparathyroidism, pregnancy-induced osteoporosis, and vitamin D deficiency in pregnancy. Endocrinol Metab Clin North Am 2019; 48: 643-655.
  • 16.
    Kumbhojkar SV, Kale AD, Kumbhojkar VR, Desai KM. Salivary calcium as a diagnostic tool for screening of osteoporosis in postmenopausal women. J Oral Maxillofac Pathol 2019; 23: 192.
  • 17.
    Ardakani Movaghati MR, Yousefi M, Saghebi SA, Sadeghi Vazin M, Iraji A, Mosavat SH. Efficacy of black seed (Nigella sativa L.) on kidney stone dissolution: A randomized, double-blind, placebo-controlled, clinical trial. Phytother Res 2019; 33: 1404-1412.
  • 18.
    Ostovar M, Akbari A, Anbardar MH, Iraji A, Salmanpour M, Ghoran SH, et al. Effects of citrullus colocynthis L. in a rat model of diabetic neuropathy. J Integrat Med 2020; 18: 59-67.
  • 19.
    Koohi-Hosseinabadi O, Ranjbar Z, Sepehrimanesh M, AndisheTadbir A, Poorbaghi SL, Bahranifard H, et al. Biochemical, hematological, and pathological related healing effects of Elaeagnus angustifolia hydroalcoholic extract in 5-fluorouracil-induced oral mucositis in male golden hamster. Environ Sci Pollut Res Int 2017; 24: 24447-24453.
  • 20.
    Dabbaghmanesh MH, Noorafshan A, Talezadeh P, Tanideh N, Koohpeyma F, Iraji A, et al. Stereological investigation of the effect of Elaeagnus angustifolia fruit hydroalcoholic extract on osteoporosis in ovariectomized rats. Avicenna J Phytomed 2017; 7: 261.
  • 21.
    Talaei T, Edalatjoo M, Bahmanpour S, Aliabadi E. Effects of anti epileptic drugs phenytoin and phenobarbital on ossification indices of mouse femur and tibia and the anti teratogenic effects of Folic Acid on the reduction of their effects. J Shahid Sadoughi Univ Med Sci 2005; 13: 51-57. (Persian).
  • 22.
    Zick SM, Djuric Z, Ruffin MT, Litzinger AJ, Normolle DP, Alrawi S, et al. Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects. Cancer Epidemiol Biomarkers Prev 2008; 17: 1930-1936.
  • 23.
    Stoilova I, Krastanov A, Stoyanova A, Denev P, Gargova S. Antioxidant activity of a ginger extract (Zingiber officinale). Food Chem 2007; 102: 764-770.##https://doi.org/10.1016/j.foodchem.2006.06.023.
  • 24.
    Zhang M, Zhao R, Wang D, Wang L, Zhang Q, Wei S, et al. Ginger (Zingiber officinale Rosc.) and its bioactive components are potential resources for health beneficial agents. Phytother Res 2021; 35: 711-742.
  • 25.
    da Silveira Vasconcelos M, Mota EF, Gomes-Rochette NF, Nunes-Pinheiro DC, Nabavi SM, de Melo DF. Chapter 3.18 - Ginger (Zingiber officinale Roscoe). In nonvitamin and nonmineral nutritional supplements, Nabavi SM, Silva AS, Eds. Academic Press: 2019; pp 235-239.##https://doi.org/10.1016/B978-0-12-812491-8.00034-5.
  • 26.
    Raji Y, Udoh U, Oluwadara O, Akinsomisoye O, Awobajo O, Adeshoga K. Anti-flammatory and analgesic properties of the rhizome extract of Zingiber officinale. Afric J Biomed Res 2002; 5.##https://doi.org/10.4314/ajbr.v5i3.53999.
  • 27.
    Mustafa T, Srivastava K, Jensen K. Pharmacology of ginger, Zingiber officinale. J Drug Develop 1993; 6: 25-39.
  • 28.
    Ali BH, Blunden G, Tanira MO, Nemmar A. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research. Food Chem Toxicol 2008; 46: 409-420.
  • 29.
    Naderi Z, Mozaffari-Khosravi H, Dehghan A, Fallah Hosseini H, Nadjarzadeh A. The effect of ginger (zingiber officinale) powder supplement on pain in patients with knee osteoarthritis: a double-blind randomized clinical trial. SSU J 2013; 20: 657-667.
  • 30.
    Altman RD, Marcussen KC. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum 2001; 44: 2531-2538.
  • 31.
    Rondanelli M, Riva A, Allegrini P, Faliva MA, Naso M, Peroni G, et al. The use of a new food-grade lecithin formulation of highly standardized ginger (Zingiber officinale) and acmella oleracea extracts for the treatment of pain and inflammation in a group of subjects with moderate knee osteoarthritis. J Pain Res 2020; 13: 761-770.
  • 32.
    Rahimlou M, Yari Z, Rayyani E, Keshavarz SA, Hosseini S, Morshedzadeh N, et al. Effects of ginger supplementation on anthropometric, glycemic and metabolic parameters in subjects with metabolic syndrome: A randomized, double-blind, placebo-controlled study. J Diabetes Metab Disord 2019; 18: 119-125.
  • 33.
    de Lima RM, Dos Reis AC, de Menezes AA, Santos JV, Filho JW, Ferreira JR, et al. Protective and therapeutic potential of ginger (Zingiber officinale) extract and.
  • 34.
    Morvaridzadeh M, Fazelian S, Agah S, Khazdouz M, Rahimlou M, Agh F, et al. Effect of ginger (Zingiber officinale) on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials. Cytokine 2020; 135: 155224.
  • 35.
    Srinaath N, Balagangadharan K, Pooja V, Paarkavi U, Trishla A, Selvamurugan N. Osteogenic potential of zingerone, a phenolic compound in mouse mesenchymal stem cells. Bio Factors 2019; 45: 575-582.
  • 36.
    Zang L, Kagotani K, Nakayama H, Bhagat J, Fujimoto Y, Hayashi A, et al. 10-Gingerol suppresses osteoclastogenesis in RAW264.7 cells and Zebrafish osteoporotic scales. Front Cell Dev Biol 2021; 9.
  • 37.
    Ito S, Ohmi A, Sakamiya A, Yano T, Okumura K, Nishimura N, et al. Ginger hexane extract suppresses RANKL-induced osteoclast differentiation. Biosci Biotechnol Biochem 2016; 80: 779-785.

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