Journal of Semnan University of Medical Sciences
Outline
A comparative study on the effects of fluoxetine and tamoxifen on the treatment of mastalgia: A randomized clinical trial
Authors
, Mohammad Reza Mohammadi Hassan, Maryam Mortazavi Lahijani, reza vazirinejad, Amir Moghadam-Ahmadi,*Abstract
Introduction: Mastalgia is a common complaint among women that requires proper medical treatment. The aim of this study was to investigate the comparison of fluoxetine versus tamoxifen effects on the mastalgia. Materials and Methods: In this clinical trial, 62 women, who referred to surgical clinic of Rafsanjan Ali-Ibn Abi-Talib hospital in 2017, with a complaint of breast pain were selected and treated with fluoxetine or tamoxifen. Correspondingly, informed consent, demographic checklists and the visual scale of the pain were completed in pre-treatment and then 4, 8 and 12 weeks after the treatment. Results: There was no significant difference between two groups in body mass index, duration of illness and duration of pain (P>0.05). Both fluoxetine and tamoxifen significantly reduced pain (P0.05). Conclusion: Both fluoxetine and tamoxifen were equally effective as alternative therapies against mastalgia
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Copyright
© 2020, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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