Satisfaction of patients in methadone maintenance treatment is one of the key options in the quality of treatment. In addition, an individual desire to be treated at these centers can contribute to his satisfaction and better social performance (
16). The drug strongly affects the metabolism of the body due to the fact that it leads to malnutrition in people (
17,
18). Several studies have reported reduced food intake and malnutrition in addicted individuals (
19,
20). Using opiates and heroin in short term leads to dryness of the mouth, and a feeling of heaviness in the limbs, nausea, vomiting, and severe itching (
21). All these symptoms can affect the nutrition of the person, leading to weight loss and malnutrition in the long-term.
Malnutrition among drug addicts varies from 5% to 30% (
20). In addition, it is reported that treatment with methadone (MMT) is useful in the treatment of dependence on opiates. Many of its effects are similar to those of other drugs such as heroin and morphine with a longer duration of effect. Drug addicts are at risk of malnutrition and now, there is little information regarding the nutrition state in these patients during methadone maintenance treatment. However, taking methadone in people leaves a good physical effect on them (
22). The lack of treatment of alcohol and drug abuse is the major cause of metabolic abnormalities and changes in the life style of people. In a study conducted in 1991 to examine the effects of nutrition treatment added to a traditional rehab program based on the 12-step alcoholics anonymous program, the results showed that the group received nutrition treatment, based on the individual nutrition advice and improved menus, and showed less symptoms of low blood sugar, blood sugar, and craving of alcohol use. Therefore, the inclusion of a therapeutic nutrition program can be effective in improving the process of NA addiction treatment process (
23).
Although in methadone maintenance treatment the drug is effective in reducing the use of heroin and other behaviours, a number of clients leave the MMT prematurely. In fact, patients who are under the monitoring system control their behaviour (
24). Furthermore, conducting drug tests regularly and the presence of laws prevent the communication of the person with other offenders and will cause the person to not be viewed equally with other offender addicted people, which improves the social health of the person (
23). In 2011, a study was conducted to examine the impact of 12-step treatment on heroin-addicted people, who were treated with methadone. Results showed that people achieved a sense of self-efficacy and were motivated to change their life style (
25). Spirituality changes in people who are treated with NA improve their control in the treatment of drug use. Although the results of the studies have shown that a significant correlation was found between spirituality and mental health of the people in the treatment stages using AA method, this process requires people completing the 12-steps treatment so that they can advocate it for others (
26). Therefore, this case could be one of the weaknesses of the study, since this study was conducted on people who received NA, in which people were treated for 6 months. Studies have also suggested that during treatment with methadone, spiritual interventions should be long enough to have the necessary effectiveness, because addiction is a chronic disease and spirituality of the person needs to be improved through his family and community interventions (
27).
The results of various studies on these anonymous groups confirm the importance of these groups in providing guidelines for life, increasing social support network, and reducing the harms related to AIDS and its related risks (
28,
29). A few studies have been conducted so far on the presence of this group of people in NA groups. Poverty, homelessness, and infections such as AIDS and hepatitis, low appetite, and the desire to withdraw from treatment are major obstacles in the treatment of NA. Therefore, therapist professionals should provide the conditions for participation of the people with AIDS in 12 sessions (
30,
31). MMT is currently widely performed in Iran, and it is expected to be effective in various aspects such as improving the physical health of the clients (
32). Some studies found this expectation. In addition, from the point of view of customers, this treatment has various successes, such as reducing the incidence of HIV, hepatitis C and other blood diseases, improved family life, finding jobs, and more support of their children. Giacomuzzi et al., showed that public health increased significantly after 6 months by using methadone (
10). In the study conducted by Kheradmand et al., in Iran in 2010 to examine the effect of maintenance treatment on the physical health of clients, results showed that improved appetite and weight is one of the beneficial effects of methadone maintenance treatment in some customers. In addition, if the patients experience reduced appetite and weight loss at the beginning of treatment, it can be due to side effects of depression and other psychiatric problems, which will be resolved by referring to a psychiatrist and prescribing a drug (
22). The reduced harm caused by the drugs is the most important goal of leaving methadone, and if it is used in an appropriate way, non-pharmaceutical side effects of MMT could reduce environmental damage and prevent accidents and diseases. Several studies have reported the role and effects of MMT on increasing the quality of the life style of patients (
33). Significant improvement will be seen in addicted patients at least 3 months after the completion of treatment (
34). Reduced harm, reduced dependency on drugs, reduced impact of diseases, and reduced use of syringes, needles, as well as injections, in order to prevent the progression of AIDS, are the main non-pharmaceutical goals of treatment with methadone (
35). Therefore, drug treatment programs pave the way for treatment of addicted people suffering from HIV infection (
36). Morata et al., analysed the impacts of needle and syringe, and methadone maintenance treatment on the prevalence rate of AIDS in Europe for 16 years. Their results indicated that participation in MMT program not only protects the human rights and health of people, but also enhances the health and wellbeing of the communities, leading to a reduced rate of the AIDS virus (
37). Changing the environment is the most important factor reducing the addiction recurrence. The addicted person uses the drug with his friends, while in methadone treatment, he uses it in the presence of the therapist and this change in the environment changes the personality and environment health of the person dramatically. Reduced physical harm, returning to normal life, job stability, and the prevention of injection are the most important benefits of environmental health in treatment with methadone. Low sexual satisfaction in 2 groups can be caused by a variety of factors, including the negative long-term impact of prolonged use of opiates on an individual’s libido, which can play a key role in reducing sexual satisfaction, which requires more treatments such as drug treatment and involvement of the couple in psychological interventions (
38). In addition, studied patients may experience lack of sexual satisfaction at the beginning and their sexual satisfaction may reach a lower level due to exposure to these groups. On the other hand, these people may be at the initial stage of a membership in this group (Narcotics Anonymous and methadone treatment), therefore, we cannot report this result definitely, due to the weakness in collecting demographic information. The strength of this study is comparing 2 successful drug-leaving methods in the world. However, its weaknesses and limitation included lack of controlling the effect of confounding factors, for example addiction history, cultural and economic differences of the addicted people, as well as using only male participants in this study.