Image Credit:Shiraz E-Med J
Outline
Effect of Measles Virus Antibodies from Breast Milk of Nursing Mothers on Seroconversion of Children After Measles Vaccination
Authors
Abstract
The effects of measles virus (MV) antibodies (abs) in the sera and breast milk of nursing and lactating mothers on sericonversion to measles vaccination was studied. Three hundred and ninty six samples were collected each from sera and breast milk of nursing mothers and corresponding number of finger prick prevaccination sera samples on filter paper from their children were tested for MV abs. Eighty (20.2%) mothers had measles haemagglutination inhibition (HI) abs in their sera and 88(27.2%) had MV HI abs in their breast milk. Eight (2.0%) of the children who had prevaccination MV abs in their sera were all from MV ab negative mothers. Forty-four (37.0%) who came back for post vaccination sera seroconverted while 76 (63.3%) gave a low seroconversion rate of 37.0%. Results showed that MV abs in either sera or breast milk of mothers did not interfer with MV vaccination in their children. The low seroconversion rate obtained was due to low vaccine potency with titers ranging between (log10-1.0 – log10-2.5) TCID/per dose. This was beside other non-specific antiviral substances exhibited virus neutralizing activity.
Highlights
References
- 1.The references are available in the PDF file.
Copyright
© 2006, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
Seroprevalence of measles, mumps and rubella Antibodies in 18 months and 6.5 years old children: 6 months after measles-mumps-rubella (MMR) vaccination
Shamsizadeh A, Nikfar R, Makvandi M, Hakimzadeh M, Alisamir M, et al. Seroprevalence of measles, mumps and rubella Antibodies in 18 months and 6.5 years old children: 6 months after measles-mumps-rubella (MMR) vaccination. Jundishapur J Microbiol. 2012;5(4):578-581. doi: https://doi.org/10.5812/jjm.4563
Seroprevalence of Measles and Rubella IgG Antibodies in Children and Pregnant Women in Iran
Rafiei Tabatabaei S, Karimi A, Alebouyeh M, Zahed G, Faghihian E, et al. Seroprevalence of Measles and Rubella IgG Antibodies in Children and Pregnant Women in Iran. Arch Pediatr Infect Dis. 2024;12(2):e140365. doi: https://doi.org/10.5812/apid-140365
Serological Response to Measles Revaccination in a Small Population After a Mass Measles Revaccination Program
Shirvani F, Tabatabaee P, Shiari R, Shiwa F, Soltanzadeh M. Serological Response to Measles Revaccination in a Small Population After a Mass Measles Revaccination Program. J Compr Ped. 2012;3(1):7-11. doi: https://doi.org/10.17795/compreped-7144
Post-Vaccination Immunity Against Measles in Under Twenty-Five-Year-Old Population of Ahvaz, Southwest of Iran
Shakurnia A, Alavi SM, Norouzirad R, Sarajian AA, Shakerinejad G. Post-Vaccination Immunity Against Measles in Under Twenty-Five-Year-Old Population of Ahvaz, Southwest of Iran. Jundishapur J Microbiol. 2013;6(10):e7707. doi: https://doi.org/10.5812/jjm.7707
Hepatitis B Seroconversion Rate After Primary Immunization Series with Newly Introduced Pentavalent Vaccine: A Report of Local Study in Alborz Province, Iran, 2016
Arjmand R, Gholami M, Shirvani F, Pourrostami K, Safari O, et al. Hepatitis B Seroconversion Rate After Primary Immunization Series with Newly Introduced Pentavalent Vaccine: A Report of Local Study in Alborz Province, Iran, 2016. Arch Pediatr Infect Dis. 2019;7(2):e83565. doi: https://doi.org/10.5812/pedinfect.83565
- Scopus by DOI: 0
Last Update: 1 month ago
- Scopus by Title: 0
Last Update: 1 month ago
- Scopus by Title (Ref): 1
Last Update: 1 month ago
- CrossRef: 0
Last Update: 5 days ago
- OpenAlex: 0
Last Update: 1 hour ago
- OpenCitations: 0
Last Update: 2 days ago