Comparison of Hemorrhoid Sclerotherapy Using Glucose 50% vs. Phenol in Olive Oil

Background: Sclerotherapy is a safe hemorrhoid treatment with minimum costs and side effects. The expensive present sclerosants reduce our tendency to use this technique, so we conducted this study in a try to replace them.

Patients and Methods: This is a prospective study on 170 hemorrhoid cases visited at Imam Ali and Khatam clinics during a year. Patients were randomly divided into case and control groups. After sedation and proctoscopy 3 ml of “50% glucose” and “phenol in olive oil” solutions were injected in each hemorrhoid pile of case and control groups respectively. Patients were assessed 1 week and 3 months thereafter. Data was analyzed via SPSS-17 software, using χ2 and t-student tests.

Results: Out of 71 cases and 73 controls, 55.6% were female. The most common chief complaint was bleeding (51.4%). The 2 groups were even regarding gender, age and chief complaint. (p-value respectively 0.412, 0.876, 0.146). Bleeding after1 week and 3 months and response rate didn’t show a significant statistical difference between 2 groups. (p- value respectively 0.914, 0.731, 0.422). Finally 19 patients didn’t respond to any treatment (13.2%).

Conclusions: In an even sample sclerotherapy with 50% glucose can be as efficient as phenol in olive oil solution. Regarding cultural characteristics, we hope that evolving non surgical techniques may encourage patients to seek early treatments.