Cover image of the article: The Effects of Three Sessions of Running on a Negative Slope on Serum Levels of Liver Enzymes in Adult Male Rats

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The Effects of Three Sessions of Running on a Negative Slope on Serum Levels of Liver Enzymes in Adult Male Rats

Authors

Mohsen Rezaei1,*, eskandar rahimi1, somayeh bordbar1, Sahar Namdar1
1Department of Exercise Physiology, Fars Sciences and Research Branch, Islamic Azad University, Shiraz, Iran
*Corresponding Author: Department of Exercise Physiology, Fars Sciences and Research Branch, Islamic Azad University, Shiraz, Iran Email: rezaei.mohsen60@yahoo.com

Zahedan Journal of Research in Medical Sciences:Vol. 15, issue 5; e92989
Published online:Nov 18, 2012
Article type:Brief Report
Received:Aug 22, 2011
Accepted:May 06, 2012
How to Cite:Rezaei M, rahimi E, bordbar S, Namdar S. The Effects of Three Sessions of Running on a Negative Slope on Serum Levels of Liver Enzymes in Adult Male Rats. Zahedan J Res Med Sci. 2013;15(5):e92989. doi:

Abstract

Background: The purpose of this study was to investigate the effects of three sessions of running on a negative slope (eccentric contraction) on changes of the serum levels of aspartate aminotransferase (AST) and alanin aminotransferaze (ALT) in adult male rats.
Materials and Methods: 20 adult male rats were divided randomly into two equal groups (exercise and control). Levels of AST and ALT in both groups were measured in a fasting state, 24 hours before and 24 hours after the last session of training.
Results: Exercise increased the levels of serum AST and ALT enzymes, significantly (p<0.05).
Conclusion: Eccentric exercise, without allowing enough time for returning to the pre-exercise state, leads to the damage of some body organs such as the liver.

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Copyright

© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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