Fulltext
The full text of this article is available on the PDF file.
Zahedan Journal of Research in Medical Sciences
The Official Journal of Zahedan University of Medical Sciences
e-ISSN 2383-2894
Image Credit:Zahedan J Res Med Sci
Outline
Comparing high dose vitamin B6 with corticotherapy in infantile spasm
Authors
1Pediatric disease dept, Faculty of medicine, Zahedan University of Medical Sciences and health services, Zahedan, Iran.
2Pediatric disease dept, Faculty of medicine, Shahid Beheshti University of Medical Sciences and health services, Tehran, Iran.
*Corresponding Author: Pediatric disease dept, Faculty of medicine, Zahedan University of Medical Sciences and health services, Zahedan, Iran. Email: shahram604@gmail.com
Published online:Sep 05, 2004
Article type:Research Article
Received:Jun 18, 2004
Accepted:Aug 25, 2004
How to Cite:Javadzadeh M, Mohavalati M, Ghofrani M. Comparing high dose vitamin B6 with corticotherapy in infantile spasm. Zahedan J Res Med Sci. 2004;6(3):e94992. doi:
Abstract
Background: Since present available treatments for infantile spasms (IS) are far from adequate,
and also side effects of the current therapeutic regimens are frequent and serious, the ongoing
search for better protocols is understandable.
Methods and Materials: We compared the therapeutic and adverse effects of vitamin B6 given in
high doses with prednisolone in a randomized controlled double blind clinical trial. Vitamin B6
(40mg/kg/24hr) and prednisolone (1.5mg/kg/day) were tried in 22 and 15 patients respectively, and
the patients were followed for at least 6 months.
Results: Response to treatment was slightly better in the prednisolone group but the difference
was not significant (P=0.4). On the other hand adverse effects were also seen more frequently with
prednisolone.
Conclusions: We conclude that high dose vitamin B6 should be looked at as a justified and worthtrying
method of treatment. It seems that it can be safely used where there is contraindication to use
other antiepileptic drugs or where they have failed, and even in fresh cases of IS.
Highlights
References
- 1.The References of this article are available on the PDF file.
Copyright
© 2004, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
28
Jan
2026
Efficacy and Safety of Pyridoxine Versus Propranolol for Pediatric Migraine Prophylaxis: A Randomized Controlled Trial
Fakhreddin Shariatmadari,
Ali Motafakker Azad,
Parsa Yousefichaijan,
Masoud Rezagholizamenjany
Shariatmadari F, Motafakker Azad A, Yousefichaijan P, Rezagholizamenjany M. Efficacy and Safety of Pyridoxine Versus Propranolol for Pediatric Migraine Prophylaxis: A Randomized Controlled Trial. Jundishapur J Chronic Dis Care. 2026;15(1):e166715. doi: https://doi.org/10.5812/jjcdc-166715
3
Apr
2023
Comparison of the Effect of Oral Versus Parenteral Vitamin D on Serum Levels of Vitamin D in Premature Infants with Vitamin D Deficiency
Mandana Kashaki,
Zohreh Mohammadi,
Ali Mazouri,
Elahe Norouzi
Kashaki M, Mohammadi Z, Mazouri A, Norouzi E. Comparison of the Effect of Oral Versus Parenteral Vitamin D on Serum Levels of Vitamin D in Premature Infants with Vitamin D Deficiency. J Compr Ped. 2023;14(2):e134297. doi: https://doi.org/10.5812/compreped-134297
28
Sep
2016
Effect of vitamin B6 on mastalgia: A double blind clinical trial
Setareh Soltany,
Hamid reza hemmati,
Rahimeh Eskandarian,
Enayatollah Gholamaliyan
Soltany S, hemmati HR, Eskandarian R, Gholamaliyan E. Effect of vitamin B6 on mastalgia: A double blind clinical trial. koomesh. 2016;17(4):e151189. doi:
16
Feb
2021
Therapeutic Efficacy of Vitamin A in the Treatment of Idiopathic Microscopic Hematuria in Children
Parsa Yousefichaijan,
Masoud Rezagholizamenjany,
Fatemeh Dorreh,
Hassan Taherahmadi,
Mohamad Rafiei,
Saeide Abbasi
,et al.Yousefichaijan P, Rezagholizamenjany M, Dorreh F, Taherahmadi H, Rafiei M, et al. Therapeutic Efficacy of Vitamin A in the Treatment of Idiopathic Microscopic Hematuria in Children. Nephro-Urol Mon. 2021;13(1):e111783. doi: https://doi.org/10.5812/numonthly.111783
26
Jan
2020
Evaluation the Efficacy of Vitamin D Consumption on Nephrotic Syndrome Condition in Children: A Clinical Trial Study
Hassan Taherahmadi,
Parsa Yousefichaijan,
Masoud Rezagholizamenjany,
Fatemeh Dorreh,
Mohammad Ahangar Davoodi,
Shahriar Hassanzadeh
Taherahmadi H, Yousefichaijan P, Rezagholizamenjany M, Dorreh F, Ahangar Davoodi M, et al. Evaluation the Efficacy of Vitamin D Consumption on Nephrotic Syndrome Condition in Children: A Clinical Trial Study. Nephro-Urol Mon. 2020;12(1):e97001. doi: https://doi.org/10.5812/numonthly.97001
Cited by
- Scopus by DOI: 0
Last Update: 3 weeks ago
- Scopus by Title: 0
Last Update: 3 weeks ago
- Scopus by Title (Ref): 0
Last Update: 3 weeks ago
- CrossRef: 0
Last Update: 8 hours ago
- OpenAlex: 0
Last Update: 11 hours ago
- OpenCitations: 0
Last Update: 4 days ago
Comments
Number of Comments:0