Central Nervous System Toxicity After Botulinum Neurotoxin Injection

Authors

Yashar Ilkhchoui1,*, Ramsis F. Ghaly2, N. Nick Knezevic2, Kenneth D Candido2
1Department of Anesthesiology and Critical Care Medicine, School of Medicine, University of New Mexico, Albuquerque, USA
2Department of Anesthesiology and Pain Management, Advocate Illinois Masonic Medical Center, Chicago, USA
*Corresponding Author: Department of Anesthesiology and Critical Care Medicine, School of Medicine, University of New Mexico, Albuquerque, USA. Tel: +1-5052722610, Fax: +1-5052721300, [email protected]. Email: [email protected]

Anesthesiology and Pain Medicine:Vol. 3, issue 1; 223-5
Published online:Jun 30, 2013
Article type:Case Report
Received:Nov 28, 2012
Accepted:Jan 13, 2013
How to Cite:Ilkhchoui Y, Ghaly RF, Knezevic NN, Candido KD. Central Nervous System Toxicity After Botulinum Neurotoxin Injection. Anesth Pain Med. 2013;3(1):. doi: https://doi.org/10.5812/aapm.9356

Abstract

Since Its first description of botulism toxicity in 1820s, specific formulations of botulinum neurotoxin (BoNT) have been introduced with different clinical benefits. However, there is increasing number of adverse events reported to Food and Drug Administration. This report presents the case of 62-year-old woman with Parkinsons disease who received BoNT injections to treat painful spasticity in her hands. She developed severe generalized dystonia shortly after BoNT injections.

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