Evaluation of Antioxidant Properties of Elaeocarpus ganitrus Roxb. Leaves

authors:

avatar T. Sathish Kumar 1 , avatar S. Shanmugam 1 , avatar T. Palvannan 2 , avatar V. M. Bharathi Kumar 1 , *

Department of Biotechnology, Kumaraguru College of Technology, Coimbatore 641 006, India
Department of Biochemistry, Periyar University, Salem 636 011, India

how to cite: Sathish Kumar T, Shanmugam S, Palvannan T, Bharathi Kumar V M. Evaluation of Antioxidant Properties of Elaeocarpus ganitrus Roxb. Leaves. Iran J Pharm Res. 2008;7(3):e128593. https://doi.org/10.22037/ijpr.2010.767.

Abstract

Ethanolic extract of leaves of Elaeocarpus ganitrus was analyzed for their total antioxidant capacity, reducing power, metal chelating, ABTS+ (2, 2-azinobis-(3-ethylbenzothiazoline-6-sulphonate) radical scavenging and hydroxyl radical scavenging activities. The extract at 500 µg/ml showed maximum Iron chelating activity (76.70%) followed by the scavenging of the ABTS+ radical (55.77%) at the same concentration. However, the extract showed only moderate hydroxyl radical scavenging activity (13.43%). Total antioxidant capacity was found to be 24.18 mg ascorbic acid equivalents at 500 µg/ml extract concentration. There was a positive correlation between the total phenolic content and antioxidant capacity, R2 = 0.8547, whereas the correlation between the total flavonoids and antioxidant capacity was determined to be R2=0.8413. The results suggest that phenolics and flavonoids in the leaves provide substantial antioxidant activity.