Kawasaki Disease

authors:

avatar Ahmad Siadati 1 , * , avatar Farah Sabouni 2 , avatar Parisa Saleh Anaraki 2 , avatar 3

Department of Pediatrics, Tehran University of Medical Sciences and Health Services, [email protected], IRAN
Department of Pediatrics, Tehran University of Medical Sciences and Health Services, IRAN

how to cite: Siadati A, Sabouni F, Saleh Anaraki P, . Kawasaki Disease. J Compr Ped.1(1): 9-23.

Abstract

Kawasaki disease is an acute vasculitis of childhood that predominantly affects the coronary arteries. The etiology of Kawasaki disease remains unknown, although an infectious agent is strongly suspected based on clinical and epidemiologic features. A genetic predisposition is also likely, based on varying incidences among ethnic groups, with higher rates in Asians. Symptoms include fever, conjunctival injection, erythema of the lips and oral mucosa, rash, and cervical lymphadenopathy. Some children with Kawasaki disease develop coronary artery aneurysms or ectasia, ischemic heart disease, or sudden death. Kawasaki disease is the leading cause of acquired heart disease among children in developed countries. This article provides a summary of the history, etiology, clinical diagnosis, treatment guidelines and lifelong follow up of KD.

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