Preventive effects of an oral rinse Peppermint essence on chemotherapy-induced oral mucosistis

How to Cite:Tahereh AshktorabZahra YazdaniFaraz MojabHamid Alavi MajdHosein MadaniPreventive effects of an oral rinse Peppermint essence on chemotherapy-induced oral mucosistis.koomesh.12(1):e152429.

Abstract

Introduction: Oral mucositis (OM) is a significant and frequent complication of chemotherapy, which results in delayed or incomplete chemotherapeutic management. This study was conducted to determine the effects of an oral rinse Peppermint essence (PE) in the prevention of chemotherapy- induced OM Materials & Methods: In this double blind clinical trial, 40 patients with colon or rectum cancers, who admitted for chemotherapeutic management, randomly divided in two equal placebo and PE groups. PE and placebo groups were received 10 drops of oral rinse PE or placebo, three times a day, from the first day of chemotherapy up to the fourteenth day, respectively. A bipartite questionnaire was used for obtaining demographic and clinical information. The evaluation of OM was measured using the WHO scale. Content and inter-rater methods were used for validity and reliability of tools, respectively (r = 0.93). Results: The incidence of OM between the PE group (15%) and the placebo group (50%) was significantly different (p

Keywords

Peppermint essence, Mouthwash, Prophylaxis, Oral mucositis, Chemotherapy

اسانس نعناع، دهانشویه، پیشگیری، موکوزیت دهانی، شیمیدرمانی

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