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Official Journal of Research Center for Gastroenterology and Liver Diseases
e-ISSN 1735-3408
p-ISSN 1735-143X
The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran
Authors
1Department of Epidemiology, School of Public Health, Fudan University, The Key Laboratory of Public Health Safety of Ministry of Education, Shanghai, China
2Department of Epidemiology, School of Public Health, University of California, Los Angeles, USA
*Corresponding Author: Na He, Department of Epidemiology, School of Public Health, Fudan University, and The Key Laboratory of Public Health Safety of Ministry of Education, Shanghai 200032, China. Tel: +86-2154237519, Fax: +86-2154237519, Email: nhe@shmu.edu.cn
Published online:May 31, 2011
Article type:Research Article
Received:Aug 11, 2010
Accepted:Nov 24, 2010
How to Cite:Liu X, Fu Z, Duan S, Gao M, He N, et al. The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran. Hepat Mon. 2012;12(7):. doi: https://doi.org/10.5812/hepatmon.6160
Abstract
Background: Hepatitis B virus (HBV) infection is a significant health problem throughout the world.
Objectives: We aimed to evaluate the prevalence of hepatitis B antigen (HBsAg) seropositivity in the general population of Mashhad, northeast of Iran.
Patients and Methods: One thousand six hundred fifty-two healthy individuals aged 1 to 90 (Mean; 29.1 ± 18.5) from all 12 municipalities of Mashad were selected randomly by multistage cluster sampling. Informed consent was obtained, and demographics and medical histories were collected. Twice-reactive samples were considered HBsAg-positive by ELISA. Chi-square test and logistic regression were applied to analyze the factors related to HBsAg positivity using SPSS 16.0.
Results: The overall prevalence of HBsAg positivity was 1.39% (95% CI, 0.91% to 2.12%); 2.0% and 0.89% among men and women, respectively (p = 0.054). Infection was more prevalent in older (p = 0.019) and married persons (p = 0.001), Afghanis (p = 0.046), and those with a history of traditional cupping (p = 0.005). There was no association between HBV infection and gender; literacy; income; employment; family size; or history of blood transfusion, dental procedure, surgery, hospitalization, or tattooing. By logistic regression analysis, age was the only variable that had a significant association with infection (p = 0.026).
Conclusion: It seems that the prevalence of HBV infection in Mashhad is slightly lower than that of the nation.
©2011 Kowsar M.P.Co. All rights reserved.
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Copyright
© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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