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Hepatitis Monthly
Official Journal of Research Center for Gastroenterology and Liver Diseases
The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran
Author(s):
Farhad Fathimoghaddam, Hamid Reza Bidkhori, Sanaz Ahmadi, Hamid Reza Sima, Mohammadreza Hedayati-Moghaddam1,*1Research Center for HIV/AIDS, HTLV and Viral Hepatitis, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, IR Iran
*Corresponding Author: Research center for HIV/AIDS, HTLV and Viral Hepatitis, Central Organization of ACECR-Mashhad, University Campus, Azadi Sq., P.O.Box: 91775-1376, Mashhad, IR Iran. Tel: +98-5118821533, Fax: +98-5118810177. Email: [email protected]
Published online:May 31, 2011
Article type:Research Article
Received:Aug 11, 2010
Accepted:Nov 24, 2010
How to Cite:Fathimoghaddam F, Bidkhori HR, Ahmadi S, Sima HR, Hedayati-Moghaddam M. The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran. Hepat Mon. 2011;11(5):. doi:
Abstract
Background: Hepatitis B virus (HBV) infection is a significant health problem throughout the world.
Objectives: We aimed to evaluate the prevalence of hepatitis B antigen (HBsAg) seropositivity in the general population of Mashhad, northeast of Iran.
Patients and Methods: One thousand six hundred fifty-two healthy individuals aged 1 to 90 (Mean; 29.1 ± 18.5) from all 12 municipalities of Mashad were selected randomly by multistage cluster sampling. Informed consent was obtained, and demographics and medical histories were collected. Twice-reactive samples were considered HBsAg-positive by ELISA. Chi-square test and logistic regression were applied to analyze the factors related to HBsAg positivity using SPSS 16.0.
Results: The overall prevalence of HBsAg positivity was 1.39% (95% CI, 0.91% to 2.12%); 2.0% and 0.89% among men and women, respectively (p = 0.054). Infection was more prevalent in older (p = 0.019) and married persons (p = 0.001), Afghanis (p = 0.046), and those with a history of traditional cupping (p = 0.005). There was no association between HBV infection and gender; literacy; income; employment; family size; or history of blood transfusion, dental procedure, surgery, hospitalization, or tattooing. By logistic regression analysis, age was the only variable that had a significant association with infection (p = 0.026).
Conclusion: It seems that the prevalence of HBV infection in Mashhad is slightly lower than that of the nation.
©2011 Kowsar M.P.Co. All rights reserved.
Copyright
© 2011, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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