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International Journal of Cancer Management
The Official Journal of Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences
e-ISSN 2538-497X
p-ISSN 2538-4422
A Study of Contractility of Proximal Surgical Margin in Esophageal Cancer
Authors
Jalaluddin Khoshnevis1,*, Afshin Moradi2, Eznollah Azargashb3, Barmak Gholizade1, Mohammad Reza Sobhiyeh1
1Cancer Research Center, Shahid Beheshti University of Medical Sciences, Dept. of General and Vascular Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3Cancer Research Center, Shahid Beheshti University of Medical Sciences, Dept. of Health and Social Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
*Corresponding Author: Corresponding author: Jalaluddin Khoshnevis, Cancer Research Center, Shahid Beheshti University of Medical Sciences, Dept. of General and Vascular Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Tel: +98-2122749214, E-mail: Email: khoshnevis.j@gmail.com
Published online:Mar 30, 2013
Article type:Research Article
Received:Sep 22, 2012
Accepted:Nov 18, 2012
How to Cite:Khoshnevis J, Moradi A, Azargashb E, Gholizade B, Sobhiyeh MR. A Study of Contractility of Proximal Surgical Margin in Esophageal Cancer. Int J Cancer Manag. 2013;6(1):e80380. doi:
Abstract
Background: The marginal length from main tumor in esophageal cancer is a considerable issue regarding surgical management and adjuvant treatment; so we decided to study the contractility effect on the proximal surgical margin after immersing it in10% buffered formalin as a fixative.
Methods: The proximal marginal length of ten sequential patients with esophageal cancer who underwent transhiatal esophagectomy were studied, on the operating table as fresh specimens, immediately after resection, and next 24, 48 and 72 hours after immersing in 10% buffered formalin.
Results: The contraction continued through the day 3, the mean contractility after one day was about 27%, after two days was 33% and after three days was 38%.
Conclusion: This study shows how the proximal esophageal margin can vary by the time, after immersing in 10% buffered formalin and should be considered in every settings and reporting documents by pathologists.
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Copyright
© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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