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International Journal of Cancer Management
The Official Journal of Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences
e-ISSN 2538-497X
p-ISSN 2538-4422
Virotherapy in Cancer
Authors
1Dept. of Biology, Faculty of Science, University of Zabol, Iran
*Corresponding Author: Corresponding author: Gholamreza Motalleb, Dept. of Biology, Faculty of Science, University of Zabol, Iran, Tel: +98-5422242503, E-mail: Email: reza.motaleb@uoz.ac.ir
Published online:Jun 30, 2013
Article type:Review Article
Received:Jan 17, 2013
Accepted:Apr 08, 2013
How to Cite:Motalleb G. Virotherapy in Cancer. Int J Cancer Manag. 2013;6(2):e80409. doi:
Abstract
New cancer therapies with novel mechanisms and functions are needed to treat patients with different cancers. Virotherapy is a good scenario for such treatment. The advantages of virotherapy include the potential lack of cross resistance with standard therapies and the ability to cause tumor destruction by numerous mechanisms. Oncolytic virus not only possesses unique mechanisms of action that are distinct from other treatment modalities, its self-perpetuating nature provides an ideal platform for therapeutic transgenic insertion. In this review article, a variety of oncolytic viruses in cancer gene therapy will be described.
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Copyright
© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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