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International Journal of Cancer Management
The Official Journal of Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences
e-ISSN 2538-497X
p-ISSN 2538-4422
Breast Cancer Biomarker Discovery: Proteomics and Genomics Approaches
Authors
1Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
*Corresponding Author: Corresponding author: MohammadEsmaeil Akbari, Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Tel: +98-2122748001-2, E-mail: Email: [email protected]
Published online:Dec 30, 2013
Article type:Review Article
Received:Sep 27, 2012
Accepted:Nov 19, 2012
How to Cite:Safaei A, Rezaei‐Tavirani M, Sobhi S, Akbari M. Breast Cancer Biomarker Discovery: Proteomics and Genomics Approaches. Int J Cancer Manag. 2013;6(Supplement):e80465. doi:
Abstract
Breast cancer is one of the major health problems of the Eastern world. Regardless of the survival rate improvement with progression in screening and adjuvant systemic therapies, still one – third of the patients with primary breast cancer have recurrence of micro metastasis after 10 years. It is important to discover a reliable biomarker for detection of breast cancer. The underlying molecular mechanism of the disease needs to be better understood. Allied to genomics, proteomics technologies promise to be valuable for identifying new markers that improve screening, early diagnosis, prognosis and prediction of therapeutic response or toxicity, as well as the identification of new therapeutic targets. In this review, we present proteomic and genomic sciences have been used for differential analysis of breast cancer to find molecular changes of cancer for detection candidate biomarkers.
Copyright
© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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