Posterior Urethral Valves; A single Center Experience

Alireza  Mirshemirani; Ahmad Khaleghnejad; Mohsen  Rouzrokh; Afsaneh Sadeghi; Leila Mohajerzadeh; Mustafa Sharifian

Innovative Journal of Pediatrics

The Scientific Journal of Growth & Development Research Center

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Posterior Urethral Valves; A single Center Experience

Author(s):

Alireza Mirshemirani^1,*,

Ahmad Khaleghnejad²,

Mohsen Rouzrokh³,

Afsaneh Sadeghi⁴,

Leila Mohajerzadeh⁵,

Mustafa Sharifian⁶

Innovative Journal of Pediatrics:Vol. 23, issue 5; 531-535

Published online:Aug 05, 2013

Article type:Research Article

Received:Feb 27, 2013

Accepted:May 15, 2013

How to Cite:Mirshemirani A, Khaleghnejad A, Rouzrokh M, Sadeghi A, Mohajerzadeh L, et al. Posterior Urethral Valves; A single Center Experience. Inn J Pediatr. 2013;23(5):. doi:

Abstract

Objective: Posterior urethral valves (PUV) are the most common cause of bladder outlet obstruction in infancy that impair renal and bladder function. This study was planned to evaluate and record the various clinical presentations and management, complications, and surgical management and long-term outcome of PUV. Methods: In a retrospective study, 98 patients who have been treated for PUV are evaluated in Mofid Children’s Hospital from January 2007 to December 2012. Detailed history taken and paraclinical examinations were performed in each patient and diagnosis was confirmed by voiding-cysto-urethrography (VCUG). PUV had been ablated in 62 patients by electric hook, and diversion was performed in 42 (42.85%) cases. Data were analyzed by SPSS software version18. Findings: Totally 98 patients with mean age at diagnosis 62 (±13) days were included in this study. Fifty seven cases had been catheterized within one to 6 days of life (mean age one day), PUV was ablated in 62 patients by electric hook, and diversion was performed in 42 cases. The most common symptom in our group was dribbling poor stream 51% and urinary tract infection (UTI) 40.8%. There was vesico-ureteral-reflux (VUR) in 61.2%, and hydronephrosis in 82.6%. Most common associated anomaly was kidney anomalies (multicystic kidney disease and renal agenesis/dysplasia) in 8 (8.2%) patients. Twenty patients had prenatal diagnosis of PUV. Complication occurred in three (3.1%) patients. Mortality occurred in 5 (5.1%) patients. Mean follow-up period was 3.4±1.2 years (1.5 months to 5 years). Conclusion: Urinary drainage by feeding tube in early days of infancy, followed by valve ablation is the best treatment in PUV, and urinary diversion improves the outcome. VCUG is still the gold-standard imaging modality for documenting PUVs. The factors like renal dysplasia and UTI have their role in final outcome.

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Author(s):

Alireza Mirshemirani:[PubMed][Scholar]
Ahmad Khaleghnejad:[PubMed][Scholar]
Mohsen Rouzrokh:[PubMed][Scholar]
Afsaneh Sadeghi:[PubMed][Scholar]
Leila Mohajerzadeh:[PubMed][Scholar]
Mustafa Sharifian:[PubMed][Scholar]

The Scientific Journal of Growth & Development Research Center

Outlines

Posterior Urethral Valves; A single Center Experience

Abstract

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References

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Last Update: 1 month ago

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