Innovative Journal of Pediatrics
The Scientific Journal of Growth & Development Research Center
e-ISSN 3117-5341
Image Credit:Inn J Pediatr
Outline
The Effects of Surfactant on Oxygenation in Term Infants with Respiratory Failure
Authors
Published online:Jul 23, 2013
Article type:Brief Report
Received:Aug 16, 2012
Accepted:May 31, 2013
How to Cite:Beken S, Turkyılmaz C, Koc E, M. Hirfanoglu I, Altuntas N. The Effects of Surfactant on Oxygenation in Term Infants with Respiratory Failure. Inn J Pediatr. 2013;23(4):. doi:
Abstract
Objective: The objective of the study was to evaluate the effects of exogenous surfactant on respiratory indices in term infants with respiratory failure. Methods: Consecutive 18 mechanically ventilated term infants, who received a single dose of exogenous surfactant were retrospectively included into the study. The respiratory outcome of surfactant rescue therapy was evaluated by comparing respiratory indices before and six hours after surfactant administration. Findings: Median oxygenation index (OI), mean alveolar pressure (MAP) and fraction of inspired oxygen (FiO2) values were significantly decreased (P<0.001); median arterial oxygen partial pressure (PaO2), arterial oxygen saturation (SaO2) and PaO2/FiO2 values were significantly increased six hours after surfactant treatment (P<0.001). Conclusion: Rescue therapy with surfactant was found to be effective in the improvement of early respiratory indices in term infants with respiratory failure.
Highlights
References
- 1.References are available on the PDF.
Copyright
© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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