Lactose-Free Compared with Lactose-Containing Formula in Dietary Management of Acute Childhood Diarrhea

Narges Razmkhah; Mohammadreza Modaresi; Omid Yaghin; Hossein Saneian

Innovative Journal of Pediatrics

The Scientific Journal of Growth & Development Research Center

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Abstract
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Lactose-Free Compared with Lactose-Containing Formula in Dietary Management of Acute Childhood Diarrhea

Author(s):

Narges Razmkhah¹,

Mohammadreza Modaresi²,

Omid Yaghin²,

Hossein Saneian^2,*

1Medical Students’ Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

2Department of Pediatrics, Isfahan University of Medical Sciences, Isfahan, Iran

Innovative Journal of Pediatrics:Vol. 22, issue 1; 82-86

Published online:Mar 31, 2012

Article type:Research Article

Received:Mar 17, 2011

Accepted:Nov 12, 2011

How to Cite:Razmkhah N, Modaresi M, Yaghin O, Saneian H. Lactose-Free Compared with Lactose-Containing Formula in Dietary Management of Acute Childhood Diarrhea. Inn J Pediatr. 2016;22(1):. doi:

Abstract

Objective: Few reports are available on some benefits, such as shortened duration of diarrhea and better weight gain, for lactose-free over lactose-containing formula in acute childhood diarrhea. We evaluated the effects of lactose-free formula in dietary management of acute diarrhea in formula-fed children.
Methods: This controlled-clinical trial was conducted on formula-fed children, aged 1 to 24 months, referring with acute non-bloody diarrhea (≤2 weeks). Those who had major systemic illness, severe malnutrition, severe dehydration, severe vomiting, or history of antibiotic therapy were not included. Children were allocated to receive lactose-free formula (intervention, n=37) or lactose-containing formula (control, n=34). Time to diarrhea relief and weight change were compared between the two groups after one week.
Findings: During the study, 32 male and 39 female children (7.1±3.7 months) were included. Those who received lactose-free formula had a significantly shorter time to diarrhea relief compared with the controls (1.7±0.7 vs. 2.6±0.7 days, P<0.001). Weight significantly increased in both groups, but there was no difference between the two groups in weight change (37±100 vs. 38±77 gr, P=0.673). Multivariate analysis showed that receiving lactose-free formula significantly predicted time to diarrhea relief (95% CI: 1.5 to 3.9, P<0.001) controlling for baseline characteristics.
Conclusion: Early administration of lactose-free formula for formula-fed children presenting with acute diarrhea can result in a more rapid relief of acute diarrhea and thus perhaps less mortality and morbidity. Trials with longer follow-ups are warranted to better evaluate long-term results such as weight change and feeding problems in this regard.

Keywords

Acute Diarrhea

Nutritional Management

Children

Lactose-Free Formula

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References

1.
References are available in PDF.

Therapeutic Effect of Synbiotics (Lactobacillus reuteri, Lactobacillus rhamnosus, Bifidobacterium infantis, and Fructooligosaccharides (FOS)) on Acute Non-bloody Diarrheal Episodes in Hospitalized Children Aged Between 6 - 24 Months: Randomized Double-Blind Placebo-Controlled Trial

Mehran Hakimzadeh,

Azadeh Arefian,

Mitra Ahmadi,

Hazhir Javaherizadeh

Hakimzadeh M, Arefian A, Ahmadi M, Javaherizadeh H. Therapeutic Effect of Synbiotics (Lactobacillus reuteri, Lactobacillus rhamnosus, Bifidobacterium infantis, and Fructooligosaccharides (FOS)) on Acute Non-bloody Diarrheal Episodes in Hospitalized Children Aged Between 6 - 24 Months: Randomized Double-Blind Placebo-Controlled Trial. Jundishapur J Nat Pharm Prod. 2024;19(2):e144123. doi: https://doi.org/10.5812/jjnpp-144123

25

Mar

2012

The Role of Cow’s Milk Allergy in Pediatric Chronic Constipation: A Randomized Clinical Trial

seyedMohsen Dehghani,

Bita Ahmadpour,

Mahmood Haghighat,

Sara Kashef,

Mohammad-Hadi Imanieh,

Mohammad Soleimani

Dehghani S, Ahmadpour B, Haghighat M, Kashef S, Imanieh M, et al. The Role of Cow’s Milk Allergy in Pediatric Chronic Constipation: A Randomized Clinical Trial. Inn J Pediatr. 2012;22(4):. doi:

4

Jul

2018

Diagnostic Value of Fecal Calprotectin in Response to Mother’s Diet in Breast-Fed Infants with Cow’s Milk Allergy Colitis

Pedram Ataee,

Masoumeh Zoghali,

Bahram Nikkhoo,

Ebrahim Ghaderi,

Majid Mansouri,

Rasoul Nasiri

,et al.

Ataee P, Zoghali M, Nikkhoo B, Ghaderi E, Mansouri M, et al. Diagnostic Value of Fecal Calprotectin in Response to Mother’s Diet in Breast-Fed Infants with Cow’s Milk Allergy Colitis. Inn J Pediatr. 2018;28(4):e66172. doi: https://doi.org/10.5812/ijp.66172

3

Jan

2013

Synbiotics in Children with Cow's Milk Allergy: A Randomized Controlled Trial

Hamid-Reza kianifarhr,

Hamid Ahanchian,

Zahra Nouri,

Seyed-Ali Jafari,

Toktam Moghiman,

Mohammad-Hadi Amirian

,et al.

kianifarhr H, Ahanchian H, Nouri Z, Jafari S, Moghiman T, et al. Synbiotics in Children with Cow's Milk Allergy: A Randomized Controlled Trial. Inn J Pediatr. 2014;24(1):. doi:

14

Jun

2022

The Efficacy and Safety of Enkephalinase Inhibitor Racecadotril in Treatment of Acute Diarrhea in Children: A Randomized Clinical Trial

Sheri Seyed Motahari,

Farid Imanzadeh,

Amirhossein Hosseini,

Naghi Dara,

Katayoun Khatami,

Ghazal Zahed

,et al.

Seyed Motahari S, Imanzadeh F, Hosseini A, Dara N, Khatami K, et al. The Efficacy and Safety of Enkephalinase Inhibitor Racecadotril in Treatment of Acute Diarrhea in Children: A Randomized Clinical Trial. J Compr Ped. 2022;13(2):e127104. doi: https://doi.org/10.5812/compreped-127104

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Author(s):

Narges Razmkhah:[PubMed][Scholar]
Mohammadreza Modaresi:[PubMed][Scholar]
Omid Yaghin:[PubMed][Scholar]
Hossein Saneian:[PubMed][Scholar]

The Scientific Journal of Growth & Development Research Center

Outlines

Lactose-Free Compared with Lactose-Containing Formula in Dietary Management of Acute Childhood Diarrhea

Abstract

Fulltext

References

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