Nationwide, suicide registry was started in Iran since 2002 (
4) and promoted to established ongoing registry in 2009 (
12). There is a wide range of registered suicidal behaviors in different regions of Iran that not only may show inherent discrepancy in the way people all around the country act but also may be an evidence of variations in registry of inflicted suicide subjects itself. The latter is of course a reflection of how people, including but not limited to registry staff in each sub-cultural area, may perceive, detect and report possible suicidal acts that obviously could include health center officials responsible in the registry (
13). During the registry years, there was a significant increase in registry of suicide attempts in the country, including almost all provinces, in contrast to the fact that registration and detection of completed suicide incidents showed a rather stable course; this resulted in decremented rates of fatality of registered suicidal behaviors in Iran as the registry goes on. Despite the pattern we found at the country level, the pattern was not the same in all registry points and there were several provinces with raised reported suicide fatality i.e. proportional decrease in the rate of attempted suicide incidents and/or increase in the rate of death by suicide for example in Zanjan, Kordestan, Ardebil and Golestan provinces. Every suicide registry needs to note regional beliefs and behavior on disclosure of suicide incidents that may be related to inherent stigma as well as lack of benefit and poor care services people perceive they could receive by respect from community and health services.
Malakouti el al. in a systematic review of suicide behaviors in Middle East reported the cumulative mean rate of committed suicide and suicidal attempts to be between 0.55 and 5.4 per 100000 individuals and between 0.72% and 4.2% in regional countries, respectively, and between 1.7 and 6.4 per 100000 and between 1.0% and 12.7%, respectively (
14).
Although provided statistics on suicide behaviors by the national suicide registration are somewhat far less than some highly cited epidemiological studies estimates (
3,
15-
18) and the systematic review on suicide behaviors in Iran, yet is the most comprehensive and only nationwide registry of suicide in Iran. Furthermore, we can hope that the development of this program in the future would provide more accurate estimates of suicide in Iran and we think that it could be a proper model for other countries especially in the Middle East where we share common cultural, regional and ethnical characteristics. By registration, it gives the health system the opportunity to study the course of suicide in inflicted subjects and to deliver necessary mental and social services for secondary and tertiary prevention of suicide, as well. This could be done by using data on suicide subjects at an individual level and by integrating the registry data and other information on service utilization in a systemic manner (
19).
The registry of more than a quarter of a million attempted suicides in Iran revealed that, similar to worldwide statistics, females had higher suicide and lower suicide mortality than males while in Iran the gender ratio (male to female) of attempts and completed suicides were about 3:2 and 2:3, respectively; males had an approximately 50% higher probability to die with a suicide attempt when compared to females, compared to worldwide reports of the ratio being 3:1 and 1:3, respectively, and about two hundred percent of completed suicide in men elsewhere (
20-
23). This indicates both low proportional attempts rate in females and higher fatality of suicide in females in Iran compared to global reports.
According to several other reports, the most common age groups that performed 80% of attempted suicides were teens and youth between 15 and 35 years old while older age groups consisted of a smaller portion of the subjects yet showed higher fatality if they attempted suicide (
20,
24). Increased fatality rate in older age groups highlights the importance of suicide prevention programs such as limited access to lethal poisons, medications and other tools (
25,
26) but there is also a need to be alarmed that about 70% of deaths by suicide in Iran is among teens and youth (more than 40% in ages between 15 and 24 years old) that implies the importance of public mental health promotion programs specified for them to address this issue (
27-
30). Interestingly, there was a small, but significant number of suicides in children under 14 years old that may shed light of this less studied age group in suicide studies in Iran (
31,
32).
Our findings were also in line with epidemiological studies on suicide in clinical and community-based subjects from Iran and other countries regarding higher risk of suicide fatality measured in rural subjects. In Iran, about 70% of the population resides in urban areas (
11) and regarding the rate of urban attempted suicides, there is a roughly even distribution of attempts in urban and rural areas according to population. Divorced and widow/widower marital status were also risk factors for increased suicide fatality (
33-
35). Having no job as a student, employee or homemaker were other risk factors of fatality in suicide incidents that may indicate the role of both social factors in choosing and acting on more fatal attempts and underline psychopathology that have an impact both on employment status and suicide vulnerability, simultaneously (
13,
35,
36). Medications overdose was the method of choice to attempt suicide in 84% of subjects that is ranked second as the cause of the death by suicide after hanging, which was not only ranked first as cause of death by suicide but was the most lethal suicide method in Iran (
5).
Among the most important limitations of the registry in addition to wide discrepancy of registration results across the registration centers, was critically low reported psychiatric and medical comorbidity in attempted suicides. About 6% and 2% of registered subjects reported comorbid mental and physical health problems, respectively, that is less than about 23% prevalence rate of mental disorders in Iran (
37) and also far less than reports indicating the rate of mental health problems in suicide incidents, up to 93% (
38-
40). This may be the result of registration system setup that have limitations in thorough psychiatric evaluation in all subjects and notably the stigma of having and reporting past mental health problems history as it is the case for suicide itself (
41). Approximately 5% of subjects reported previous suicide history and as the registry system lacks the ability to identify suicide history because of personal identity privacy issues, this record also has the limitations mentioned for mental and physical illness history.
We hope this study can highlight the importance of establishment and improving suicide registries in suicide prevention and surveillance programs and as indicated already there are several issues to consider when running and utilizing the registry data including cultural and stigma related factors, pattern of suicide methods prevalence and fatality in each area as well as other fatality risk factors involved in surveillance and prevention programs.