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20 resultsUpdated October 24, 2026
1

Pharmacological Inhibition of Ferroptosis as a Therapeutic Target for Neurodegenerative Diseases and Strokes

Advanced Science 10(24) (2023)

Yumin Wang; Shuang Wu; Qiang Li; Huiyan Sun; Hongquan Wang

2

Crocin molecular signaling pathways at a glance: A comprehensive review

Phytotherapy Research 36(10) (2022)

Motahareh Boozari; Hossein Hosseinzadeh

3

Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular basis to therapy

Mechanisms of Ageing and Development 205 (2022)

Maria Concetta Scuto; Sergio Modafferi; Francesco Rampulla; Vincenzo Zimbone; Mario Tomasello; Sestina Maria Spanò; Maria Laura Ontario; Agostino Palmeri; Angela Trovato Salinaro; Rosalba Siracusa; Rosanna Di Paola; Salvatore Cuzzocrea; Edward J. Calabrese; Uwe Wenzel; Vittorio Calabrese

4

The key role of the ferroptosis mechanism in neurological diseases and prospects for targeted therapy

Frontiers in Neuroscience 19 (2025)

Chenyu Xie; Nan Wu; Jiaojiao Guo; Liangliang Ma; Cong-Cong Zhang

5

Crocin induces ROS-mediated papillary thyroid cancer cell apoptosis by modulating the miR-34a-5p/PTPN4 axis in vitro

Toxicology and Applied Pharmacology 437 (2022)

Yan Tang; Han Yang; Jinsong Yu; Li Zhong; Quanxiao Xu; Bo Ding; Guangwei Jia

6

Crocin (bioactive compound of Crocus sativus L.) potently restores REM sleep deprivation-induced manic- and obsessive-compulsive-like behaviors in female rats

Behavioural Pharmacology 35(4) (2024)

Mohammad Houshyar; Hanie Karimi; Zahra Ghofrani-Jahromi; Sarah Nouri; Salar Vaseghi

7

Paradigms and Success Stories of Natural Products in Drug Discovery Against Neurodegenerative Disorders (NDDs)

Current Neuropharmacology 22(6) (2023)

Sukhwinder Singh; Shivani Chib; Md Jawaid Akhtar; Bhupinder Kumar; Bhupinder Kumar; Pooja A. Chawla; Rohit Bhatia

8

Interaction effect of crocin and citalopram on memory and locomotor activity in rats: an insight into BDNF and synaptophysin levels in the hippocampus

Naunyn-Schmiedeberg s Archives of Pharmacology 397(9) (2024)

Samineh Nasseri; Shadi Hajrasouliha; Salar Vaseghi; Batool Ghorbani Yekta

9

Transgenerational hormesis in healthy aging and antiaging medicine from bench to clinics: Role of food components

Mechanisms of Ageing and Development 220 (2024)

Vittorio Calabrese; Naomi Osakabe; Rosalba Siracusa; Sergio Modafferi; Rosanna Di Paola; Salvatore Cuzzocrea; Ursula M. Jacob; Tilman Fritsch; Ali S. Abdelhameed; Luay J. Rashan; Uwe Wenzel; Claudio Franceschi; Edward J. Calabrese

10

Modulating effects of crocin on lipids and lipoproteins: Mechanisms and potential benefits

Heliyon 10(7) (2024)

Habib Yaribeygi; Mina Maleki; Farin Rashid-Farrokhi; Payman Raise‐Abdullahi; Mohammad Amin Hemmati; Tannaz Jamialahmadi; Amirhossein Sahebkar

11

Antidiabetic and antioxidant potential of Crocin in high-fat diet plus streptozotocin-induced type-2 diabetic rats

International Journal of Immunopathology and Pharmacology 38 (2024)

Syed Mohammed Basheeruddin Asdaq; Basheerahmed Abdulaziz Mannasaheb; Raha Saud Orfali; Ibrahim Ahmed Shaikh; Ahmed Alshehri; Adel Alghamdi; Meshal Mohammed Alrashdi; Moneer E. Almadani; Faisal Mohammad Ali Abdalla

12

Crocin Improves Cognitive Impairment in LPS-treated Rats through Anti-Apoptotic, Anti-Inflammatory, and Antioxidant Activities

Molecular Neurobiology 62(5) (2024)

Maryam Dastan; Ziba Rajaei; Mohammadreza Sharifi; Hossein Salehi

13

Crocin and gallic acid attenuate ethanol-induced mitochondrial dysfunction via suppression of ROS formation and inhibition of mitochondrial swelling in pancreatic mitochondria

Molecular and Cellular Biochemistry 480(6) (2025)

Ahmad Salimi; Saleh Khezri; Mojtaba Amani; Niknaz Badrinezhad; Sahar Hosseiny; Reza Saadati

14

Crocins for Ischemic Stroke: A Review of Current Evidence

Frontiers in Pharmacology 13 (2022)

Kiran Shahbaz; Dennis Chang; Xian Zhou; Mitchell Low; Sai Wang Seto; Chung Guang Li

15

[Retracted] Helicid Improves Lipopolysaccharide‐Induced Apoptosis of C6 Cells by Regulating SH2D5 DNA Methylation via the CytC/Caspase9/Caspase3 Signaling Pathway

Contrast Media & Molecular Imaging 2022(1) (2022)

Yuan Zhang; Mei Wang; Xiaotong Zhang; Zhen-Yi Jiang; Yuanxiang Zhang; Xiangjun Fu; Yanna Li; Danping Cao; Jun Hyun Han; Jiucui Tong

16

Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer's model induced by beta-amyloid in rats.

PubMed 27(7) (2024)

Gholam Hossein Meftahi; Mohsen Khodadadi; Gila Pirzad Jahromi; Masoud Ezami; Habib Valipour

19

The Selective Cytotoxicity of Quercus Brantii Lindl. Galls on A375 and SK-MEL-3 Human Malignant Melanoma Cell Lines

Asian Pacific Journal of Cancer Prevention 24(7) (2023)

Bahareh Sadat Yousefsani; Kamyar Mohajer; Ali Qobadi; Kobra Shirani; Jalal Pourahmad

20

Saffron and its Bioactive Constituents as Mitochondria-Targeted Protectors Against Organ Injury

Molecular Neurobiology 63(1) (2026)

Fatemeh Pedramfar; Ali Abolhosseini; Cosimo D’Aiello; Vahid Pourbarkhordar; Sohrab Rahmani