Paraoxonase Inhibition by Propranolol
Authors
Abstract
There are many evidences that human serum paraoxonase activity modifies plasma lipid profile and paraoxonase has an antiatherogenic property. Non-selective beta-blockers affect plasma lipid profile too, but they have atherogenic property when patients take these drugs in long term. In this study the effect of propranolol, a non-selective beta-blocker, on paraoxonase activity was investigated. Lineweaver-Burk and secondary plots were drawn and showed that propranolol is a mixed non-competitive inhibitor of paraoxonase.
Copyright
© 2022, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
Paraoxonase and Arylesterase activities of human serum paraoxonase in coronary artery disease
Mahrooz A, Nori M, Rashidi M, AslanAbadi N, Ghojegh D, et al. Paraoxonase and Arylesterase activities of human serum paraoxonase in coronary artery disease. koomesh. 2008;10(1):e152212. doi:
Determination of serum paraoxonase phenotype distribution by double-substrate method in patients with coronary artery disease
Mahrooz A, Nori M, Rashidi M, AslanAbadi N, Ghojagh D. Determination of serum paraoxonase phenotype distribution by double-substrate method in patients with coronary artery disease. koomesh. 2011;12(3):e152455. doi:
Synthesis of Brominated 2-Phenitidine Derivatives as Valuable Inhibitors of Cholinesterases for the Treatment of Alzheimer’s Disease
Abbasi MA, Saeed A, Aziz-ur-Rehman , Mohmmed Khan K, Ashraf M, et al. Synthesis of Brominated 2-Phenitidine Derivatives as Valuable Inhibitors of Cholinesterases for the Treatment of Alzheimer’s Disease. Iran J Pharm Res. 2014;13(1):e125445. doi: https://doi.org/10.22037/ijpr.2014.1450
Enhancement of Frequency Domain Indices of Heart Rate Variability by Cholinergic Stimulation with Pyridostigmine Bromide
Zarei AA, Foroutan SA, Foroutan SM, Erfanian Omidvar A. Enhancement of Frequency Domain Indices of Heart Rate Variability by Cholinergic Stimulation with Pyridostigmine Bromide. Iran J Pharm Res. 2011;10(4):e125994. doi: https://doi.org/10.22037/ijpr.2011.987
In vitro Effects of Propofol and Bupivacaine on Pregnant Women’s Plasma Cholinesterase Activity and Malondialdehyde Level
Karam RS, Mohammad FK. In vitro Effects of Propofol and Bupivacaine on Pregnant Women’s Plasma Cholinesterase Activity and Malondialdehyde Level. J Cell Mol Anesth. 2024;9(1):e145364. doi: https://doi.org/10.5812/jcma-145364
- Scopus by DOI: 4
Last Update: 1 month ago
- Scopus by Title: 4
Last Update: 1 month ago
- Scopus by Title (Ref): 0
Last Update: 1 month ago
- CrossRef: 0
Last Update: 1 day ago