Cover image of the article: Antifungal Effect of Echinophora Platyloba' s Extract against Candida albicans

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Antifungal Effect of Echinophora Platyloba' s Extract against Candida albicans

Authors

Majid Avijgan1,*, Massoud Hafizi2, Mehdi Saadat2, Mohammad Ali Nilforoushzadeh3
1Department of Infectious and Tropical Diseases, Shahr-e-Kord University of Medical Sciences, Shahr-e-Kord, Iran
2Shahr-e-kord University of Medical Sciences, Shahr-e-Kord, Iran
3Isfahan Skin and Leishmaniasis Diseases Research Center, Isfahan, Iran
*Corresponding Author: Department of Infectious and Tropical Diseases, Shahr-e-Kord University of Medical Sciences, Shahr-e-Kord, Iran. Email:avijgan@yahoo.com

Iranian Journal of Pharmaceutical Research:Vol. 5, issue 4; 285-289
Published online:Nov 20, 2010
Article type:Research Article
Received:Oct 21, 2005
Accepted:Apr 21, 2006
How to Cite:Avijgan M, Hafizi M, Saadat M, Nilforoushzadeh MA. Antifungal Effect of Echinophora Platyloba' s Extract against Candida albicans. Iran J Pharm Res. 2022;5(4):e128301. doi: https://doi.org/10.22037/ijpr.2010.691

Abstract

The present study was undertaken to investigate the effectiveness of the ethanolic extract of Echinophora platyloba DC. on Candida albicans.

Using the agar dilution method, the growth condition of standard Candida albicans ATCC 10231, cultured on the media containing plant extracts at different concentrations (1,2,4,8,16,32,64,128 and 256 mg/ml) was studied. The results were recorded twenty one days after the incubation period, maximum time for the growth of fungi.

Results showed that the extract of Echinophora platyloba, equal or above the concentration of 2mg/ml, effectively inhibits the growth of Candida albicans. In other words it shows growth on media containing 1mg/ml of the extract.

Results of the present study revealed a great promise in the application of Echinophora platyloba extract against Candida albicans. It is concluded that the plant studied could be a good antifungal source.

Highlights

Copyright

© 2022, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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