Cover image of the article: Betamethasone Can Significantly Decrease Level of Striatal Glutamate in Animal Model of Parkinson's Disease

Image Credit:Iran J Pharm Res

Betamethasone Can Significantly Decrease Level of Striatal Glutamate in Animal Model of Parkinson's Disease

Authors

Mehdi Shafiee Ardestani1,*, Hadi Fathi-Moghaddam2
1Department of Medicinal Chemistry and Radiopharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2Department of Physiology and Physiology Research Center, Jondishapour University of Medical Sciences, Ahwaz, Iran
*Corresponding Author: Department of Medicinal Chemistry and Radiopharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. Email:shafieeardestani@gmail.com

Iranian Journal of Pharmaceutical Research:Vol. 7, issue 3; 229-232
Published online:Nov 20, 2010
Article type:Rapid Communication
Received:Nov 01, 2007
Accepted:May 01, 2008
How to Cite:Shafiee Ardestani M, Fathi-Moghaddam H. Betamethasone Can Significantly Decrease Level of Striatal Glutamate in Animal Model of Parkinson's Disease. Iran J Pharm Res. 2022;7(3):e128607. doi: https://doi.org/10.22037/ijpr.2010.770

Abstract

In the present study, the effect of steroidal anti-inflammatory drug betamethasone (0.12, 0.24 mg/kg, i.p. acutely) on striatal glutamate level in Parkinsonian rats was studied using the microdialysis technique. Our results showed significant differences (p<0.05) in the level of striatal glutamate between treated and non-treated damaged rats.

Highlights

Copyright

© 2022, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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