Cover image of the article: The Contents of Sesamol in Iranian Sesame Seeds

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The Contents of Sesamol in Iranian Sesame Seeds

Authors

Naficeh Sadeghi1, Mohammad Reza Oveisi1, Mannan Hajimahmoodi1, Behrooz Jannat2,*, Masoomeh Mazaheri1, Sadollah Mansouri3
1Drug and Food Control Department, Faculty of Pharmacy, Medical Sciences/University of Tehran, Tehran, Iran
2Food and Drug Laboratory Research Center, Ministry of Health and Medical Education, Tehran, Iran
3Seed and Plant Improvement Institute, Karaj, Iran
*Corresponding Author: Food and Drug Laboratory Research Center, Ministry of Health and Medical Education, Tehran, Iran. Email:janatbhr@sina.tums.ac.ir

Iranian Journal of Pharmaceutical Research:Vol. 8, issue 2; 101-105
Published online:Nov 20, 2010
Article type:Research Article
Received:Apr 01, 2008
Accepted:Oct 01, 2008
How to Cite:Sadeghi N, Oveisi MR, Hajimahmoodi M, Jannat B, Mazaheri M, et al. The Contents of Sesamol in Iranian Sesame Seeds. Iran J Pharm Res. 2022;8(2):e128623. doi: https://doi.org/10.22037/ijpr.2010.796

Abstract

Sesamol is a sesame lignan. Sesame lignans have multiple functions, including antioxidant activity and also seem to have potential as a source of phytostrogens. This study was condncted to evaluate sesamol contents of 7 brands of Iranian sesame seeds (Sesamum indicume L.). The brands were named Karaj 29, Darab 14, Ultan, Dezful, Varamin, Branching Naz, and Nonbranching Naz. After method validation, the methanolic extracts of seeds were investigated by HPLC. Their mean of total sesamol was found to be 4.67±0.92 mg/g (ranging between 2.75 and 6.13 mg/g). The brands Karaj 29 with 5.84±0.25 mg/g, Dezful with 5.48±0.08 mg/g, and Varamin with 5.4±0.1mg/g had the highest content, and Darab 14 with the content of 3.30±0.57mg/g had the lowest (p<0.05). Iranian sesame can be considered to be a good source of natural antioxidants for medicinal and commercial uses.

Highlights

Copyright

© 2022, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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