Cover image of the article: Pathology of Coronary Chronic Total Occlusion

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Pathology of Coronary Chronic Total Occlusion

Authors

Kenichi Sakakura1, Kazuyuki Yahagi1, Renu Virmani1, Michael Joner1,*
1CVPath Institute, Gaithersburg, United States
*Corresponding Author: Corresponding author: Michael Joner, CVPath Institute, Gaithersburg, United States Email: mjoner@cvpath.org

International Cardiovascular Research Journal:Vol. 10, issue 2; e10279
Published online:Jun 01, 2016
Article type:Review Article
Received:Jun 24, 2015
Accepted:Oct 12, 2015
How to Cite:Sakakura K, Yahagi K, Virmani R, Joner M. Pathology of Coronary Chronic Total Occlusion. Int Cardiovasc Res J. 2016;10(2):e10279. doi:

Abstract

There is an increasing need for percutaneous revascularization procedures of coronary Chronic Total Occlusion (CTO), because many patients with severe coronary artery disease have limited options for revascularization. Although the success rate of percutaneous revascularization of CTOs was unsatisfactory from the 1990s to the 2000s, recent technological advances in interventional strategies have improved the success rate to 85%. Detailed histological assessment of human autopsy studies of CTO has contributed significantly to the refinement in Percutaneous Coronary Intervention (PCI) techniques and device development. We have recently reported the pathological findings and characteristics of CTOs that occur in different clinical scenarios. In this review, we discuss the pathology of CTOs to facilitate greater understanding of revascularization strategies for CTOs.

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Copyright

© 2016, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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