Fulltext
The full text is available in PDF.
International Cardiovascular Research Journal
The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences
Outlines
The Effects of Heart-Lung Bypass on Endothelial Function of Patients with Open Heart Surgery
Author(s):
1Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
*Corresponding Author: Corresponding author: Mohammad Borzoee, Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Email: [email protected]
Published online:Jun 30, 2015
Article type:Brief Report
Received:Mar 12, 2017
Accepted:Dec 06, 2014
How to Cite:Borzoee M, Nezami AR, Ajami G, Amoozgar H, Amirghofran A. The Effects of Heart-Lung Bypass on Endothelial Function of Patients with Open Heart Surgery. Int Cardiovasc Res J. 2017;9(2):e11406. doi:
Abstract
Background: Endothelium is an essential organ for maintaining an adequate vascular tone and preventing the pathological process of atherosclerosis. Heart-lung machine is a mechanical support for maintenance of blood circulation during open heart surgery. It has been shown that flow of blood through this circuit can induce complement activation, endotoxines production, and release of many inflammatory mediators.
Objectives: Cardiopulmonary Bypass (CPB) has some detrimental effects on endothelial function. Flow Mediated Dilation (FMD) is also a noninvasive method for evaluation of endothelial function.
Patients and Methods: This study was conducted on 22 patients who were admitted in cardiac surgery ward for open heart operation and met the inclusion criteria of the study. Brachial artery FMD was measured the day before and 2 days after CPB.
Results: The mean duration of CPB was 62.95 minutes. The mean percent of FMD changes was measured and compared before and after CPB (4.29 and 0.03 vs. 1.38 and 1.99, < 0.001). The results showed a significant relationship between CPB and bronchial endothelial function.
Conclusions: This study revealed the influence of CPB on endothelial function. Yet, more studies are necessary to confirm this important issue, and decline in use of CPB is appreciated.
References
- 1.The references are available in PDF.
Copyright
© 2017, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
17
Nov
2018
Recovery of Respiratory Function After Coronary Artery Bypass Graft Surgery Using Pep-Therapy
Maxim Leonidovich Mamalyga,
Galina Vasilyevna Lobacheva,
Michael Mikhailovich Alshibaya
Mamalyga ML, Lobacheva GV, Alshibaya MM. Recovery of Respiratory Function After Coronary Artery Bypass Graft Surgery Using Pep-Therapy. Multidiscip Cardio Annal. 2019;10(1):e82822. doi: https://doi.org/10.5812/mca.82822
19
Apr
2020
Comparison of Patient’s Kidney Function Based on Kidney Disease Improving Global Outcomes (KDIGO) Criteria and Clinical Parameters in Isolated Coronary Artery Bypass Graft (CABG) Surgery in On-Pump and Off-pump Methods in Patients with Low Cardiac Output Syndrome (LCOS) After Surgery
Mehdi Fathi,
Morteza Valaei,
Amene Ghanbari,
Reza Ghasemi,
Mohsen Yaghubi
Fathi M, Valaei M, Ghanbari A, Ghasemi R, Yaghubi M. Comparison of Patient’s Kidney Function Based on Kidney Disease Improving Global Outcomes (KDIGO) Criteria and Clinical Parameters in Isolated Coronary Artery Bypass Graft (CABG) Surgery in On-Pump and Off-pump Methods in Patients with Low Cardiac Output Syndrome (LCOS) After Surgery. Anesth Pain Med. 2020;10(2):e100517. doi: https://doi.org/10.5812/aapm.100517
17
Sep
2023
The Effect of Breathing Exercises on Respiratory Condition After Coronary Artery Bypass Surgery
Hedayat Jafari,
Masoumeh Bagheri-Nesami,
Shaahin Khosravi,
Mohammad Reza Habibi,
Reza Ali Mohammadpour Tohamtan
Jafari H, Bagheri-Nesami M, Khosravi S, Habibi MR, Ali Mohammadpour Tohamtan R. The Effect of Breathing Exercises on Respiratory Condition After Coronary Artery Bypass Surgery. J Nurs Midwifery Sci. 2023;10(3):e139183. doi: https://doi.org/10.5812/jnms-139183
4
Nov
2018
The Effect of Pulsatile Blood Flow During Proximal Graft, on Liver Function in Coronary Artery Bypass Graft Surgery
Seyed Mohammadreza Amouzegar Zavareh,
Marzieh Lak
Amouzegar Zavareh SM, Lak M. The Effect of Pulsatile Blood Flow During Proximal Graft, on Liver Function in Coronary Artery Bypass Graft Surgery. J Cell Mol Anesth. 2018;3(3):e149550. doi: https://doi.org/10.22037/jcma.v3i3.17329
18
Jan
2016
Comparing the Effects of 5% Albumin and 6% Hydroxyethyl Starch 130/0.4 (Voluven) on Renal Function as Priming Solutions for Cardiopulmonary Bypass: A Randomized Double Blind Clinical Trial
Mahmood Hosseinzadeh Maleki,
Pooya Derakhshan,
Amir Rahmanian Sharifabad,
Ahmad Amouzeshi
Hosseinzadeh Maleki M, Derakhshan P, Rahmanian Sharifabad A, Amouzeshi A. Comparing the Effects of 5% Albumin and 6% Hydroxyethyl Starch 130/0.4 (Voluven) on Renal Function as Priming Solutions for Cardiopulmonary Bypass: A Randomized Double Blind Clinical Trial. Anesth Pain Med. 2016;6(1):e30326. doi: https://doi.org/10.5812/aapm.30326
Download PDF644.72 KB
Comments
Number of Comments:0Cited by
- Scopus by DOI: 0
Last Update: 1 week ago
- Scopus by Title: 0
Last Update: 1 week ago
- Scopus by Title (Ref): 0
Last Update: 1 week ago
- CrossRef: 0
Last Update: 1 day ago
Ordering Reprints
Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC
Search Relations
Author(s):
Related Articles