Image Credit:J Cell Mol Anesth
Outline
The Effect of Pulsatile Blood Flow During Proximal Graft, on Liver Function in Coronary Artery Bypass Graft Surgery
Authors
Abstract
Background: Liver dysfunction is a rare complication with high mortality and morbidity in coronary artery bypass grafting (CABG) surgery. Pulsatile blood flow probably maintains liver function during cardiopulmonary bypass (CPB).Methods: In this randomized clinical trial study, 68 patients who were underwent CABG surgery divided in two groups: pulsatile and non-pulsatile groups. We transferred continuous blood flow to pulsatile blood flow during proximal graft by using cardiac contraction.Results: There was not significant difference in serum-alanine-aminotransferase (SGPT) and alkaline phosphatase (ALP) values at variable times in two groups. In addition, the procedure of SGPT and ALP in the case and control groups was not significantly different in three days. There was not significant difference in serum glutamic oxaloacetic transaminase (SGOT) values at variable times in two groups. However, the procedure of SGOT in the case group was significantly increased and in control group was not significantly different in three days.Conclusion: we conclude that hemodynamic stability is more important than type of blood flow in maintaining liver function.Keywords: pulsatile perfusion, cardio pulmonary bypass, liver function
Highlights
References
- 1.References are in the PDF file of the article.
Copyright
© 2018, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
An Assessment of Renal Function with Pulsatile Perfusion During Proximal Graft Using Cardiac Contraction in Coronary Artery Bypass Graft Surgery
Amouzegar SM, Lak M. An Assessment of Renal Function with Pulsatile Perfusion During Proximal Graft Using Cardiac Contraction in Coronary Artery Bypass Graft Surgery. Nephro-Urol Mon. 2017;9(5):e14324. doi: https://doi.org/10.5812/numonthly.14324
Comparison of Renal Function in Coronary Artery Bypass Graft Surgery with Pulsatile versus Non-pulsatile Perfusion: A Randomized Clinical Trial
Mali S, Montazerghaem H, Salehi S, Jambarsang S, Tajamolian A. Comparison of Renal Function in Coronary Artery Bypass Graft Surgery with Pulsatile versus Non-pulsatile Perfusion: A Randomized Clinical Trial. Int Cardiovasc Res J. 2021;15(3):e112221. doi:
The Effects of Heart-Lung Bypass on Endothelial Function of Patients with Open Heart Surgery
Borzoee M, Nezami AR, Ajami G, Amoozgar H, Amirghofran A. The Effects of Heart-Lung Bypass on Endothelial Function of Patients with Open Heart Surgery. Int Cardiovasc Res J. 2017;9(2):e11406. doi:
Comparing the Effects of 5% Albumin and 6% Hydroxyethyl Starch 130/0.4 (Voluven) on Renal Function as Priming Solutions for Cardiopulmonary Bypass: A Randomized Double Blind Clinical Trial
Hosseinzadeh Maleki M, Derakhshan P, Rahmanian Sharifabad A, Amouzeshi A. Comparing the Effects of 5% Albumin and 6% Hydroxyethyl Starch 130/0.4 (Voluven) on Renal Function as Priming Solutions for Cardiopulmonary Bypass: A Randomized Double Blind Clinical Trial. Anesth Pain Med. 2016;6(1):e30326. doi: https://doi.org/10.5812/aapm.30326
Serum Lactate Is not Correlated with Mixed or Central Venous Oxygen Saturation for Detecting Tissue Hypo Perfusion During Coronary Artery Bypass Graft Surgery: A Prospective Observational Study
Shahbazi S, Khademi S, Shafa MS, Joybar R, Hadibarhaghtalab M, et al. Serum Lactate Is not Correlated with Mixed or Central Venous Oxygen Saturation for Detecting Tissue Hypo Perfusion During Coronary Artery Bypass Graft Surgery: A Prospective Observational Study. Int Cardiovasc Res J. 2017;7(4):e12363. doi:
- Scopus by DOI: 1
Last Update: 1 month ago
- Scopus by Title: 0
Last Update: 1 month ago
- Scopus by Title (Ref): 1
Last Update: 1 month ago
- CrossRef: 0
Last Update: 6 days ago
- OpenAlex: 1
Last Update: 8 hours ago
- OpenCitations: 0
Last Update: 4 days ago