Characteristics, Outcomes, and Predictors of In-Hospital Mortality in Patients Hospitalized with Acute Systolic Heart Failure (HFrEF): Two- Center Registry of Acute Heart Failure from Iran

Background:

Acute Heart Failure (AHF) is a common cause of hospitalization in many countries. Rehospitalization due to AHF is also a very important economic issue for health services. Registries for AHF have been made in many countries to characterize such patients, which have provided great information about these patients for better care. To date, there is insufficient information about these patients in Iran and their rehospitalization and short- and long-term follow-up is unclear.

Objectives:

This study aims to describe the results of a small registry of AHF (HFrEF) patients in Iran and their short-term follow-up.

Patients and Methods:

This study aimed to describe the earliest results of the AHF registry, which was started from September 2015 in two hospitals (Afshar Heart Center in Yazd and Rajaie Heart Center in Tehran). All patients with diagnosis of AHF and HFrEF were enrolled into this registry. During six months, 352 patients with diagnosis of AHF and HFrEF were entered into this registry. The patients’ demographic, clinical, and Para clinical data were collected during hospitalization and they were followed up for all-cause mortality and hospitalization for three months. Patients suffering from heart failure with preserved ejection fraction were excluded because of their small number and incomplete data.

Results:

The mean age of the patients was 55 ± 16 years and 76% were male. Besides, 77% of the patients had acute decompensation of chronic heart failure and 17% had new-onset AHF. Etiology of heart failure was ischemic heart disease in 52% of the patients. Additionally, the mean left ventricular ejection fraction was 20%. Moreover, length of hospital stay was 10.5±10 days and in-hospital mortality rate was 9.7%.

Conclusions:

This small and limited registry of patients with AHF (HFrEF) in Iran delineated these patients’ characteristics with some discrepancies and similarities with western registries. Thus, a larger nationwide registry is needed for further clarification of the issue.