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International Cardiovascular Research Journal
The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences
e-ISSN 2251-9149
p-ISSN 2251-9130
Outline
Comparison of Cord Blood Atherogenic Index in Males and Females
Authors
Published online:Mar 31, 2010
Article type:Brief Report
Received:Feb 19, 2010
Accepted:Mar 30, 2010
How to Cite:Kharb S, Kaur A, Nanda S. Comparison of Cord Blood Atherogenic Index in Males and Females. Int Cardiovasc Res J. 2010;4(1):e67666. doi:
Abstract
Background: A strong independent relationship has been observed in epidemiological studies between serum
cholesterol and coronary heart disease.
Method: Study group consisted of 100 healthy newborns and hundred healthy volunteers (age group 18-25
years) served as controls. Samples were analyzed for lipid profile (total cholesterol, triglycerides, HDL cholesterol,
VLDL cholesterol, and LDL cholesterol), apolipoproteins: ApoA-I, ApoB. Atherogenic index (A.I.)
was calculated as ratio of Apo-B to ApoA-I.
Results: Lipid profile parameters were significantly lower in cord blood as compared to adults (P<0.001),
cord blood of female newborns had higher total cholesterol (T-C), HDL-C, LDL-C Apo A-I, Apo B and A.I.
as compared to male newborns, whereas triglycerides and VLDL–C were higher in male newborns.
Conclusion: Gender-related factors might influence lipid levels and the pathological processes for CVD and
its risk factors have been rooted in childhood which can change favorably in youth with lifestyle modifications
and obesity reduction.
References
- 1.The references are available in PDF.
Copyright
© 2010, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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