Journal of Comprehensive Pediatrics
Gholamreza Soleimani
1,*, 
Simin Sadeghi Bojd1, Mahsa Tajik1, Elham Shafighi Shahri1, Somayeh Rashidi1Kawasaki disease (KD) is a vasculitis affecting multi-organ systems including liver and kidneys. KD is diagnosed by some clinical criteria including sterile pyuria, microscopic hematuria, proteinuria due to renal involvement, liver abnormalities manifesting as abnormal liver function tests, gallbladder hydrops, and hypoalbuminemia.
The aim of the study was to determine the frequency of liver and renal abnormalities in patients with KD, hospitalized in Ali-Ebne-Abitaleb Hospital of Zahedan during 2006 - 2013.
Paraclinical findings including serum and urine tests as well as gallbladder ultrasonography of 47 patients with KD hospitalized in Ali-Ebne-Abitaleb Hospital of Zahedan during 2006 - 2013 were reviewed retrospectively.
Liver abnormalities were found in 22 (46.8%) cases and impaired liver function tests were more common than other liver abnormalities in this cross-sectional study. The incidence of abnormal liver function tests in this study was about 42%. Gallbladder hydrops were found in 6 (12.7%) patients and 18 (38.3%) had renal involvement. Sterile pyuria was the most common urine abnormality with incidence of 36.2%. Microscopic hematuria and proteinuria were rarely found; in addition, serum urea nitrogen and creatinine had normal levels in all patients.
The possibility of KD should be considered in any infants or children with abnormal results in liver or renal function tests. Paraclinical findings of liver and renal involvements of all patients were partly similar to the previous studies.
© 2014, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Nasri P, Adibmajlesi Z, Rahimi H, Saneian H, Famouri F, et al. Gastrointestinal Manifestations in Children with Kawasaki Disease in Isfahan, Iran. Arch Pediatr Infect Dis. 2020;8(2):e103072. doi: https://doi.org/10.5812/pedinfect.103072
Ayazi P, Mohammadzadeh G, Arian far F. Clinical symptoms and laboratory findings of Kawasaki disease in children. J Inflamm Dis. 2024;11(1):e155279. doi:
Moradinejad MH, Kiani A. Kawasaki Disease in 159 Iranian Children. J Compr Ped. 2007;1(1):. doi:
Hosseini A, Shiari R, Bagherfar H, Rahmani K, Mofidi SA, et al. Assessment of Gastrointestinal Manifestations and Predictive Factors Associated with Their Occurrence in Kawasaki Disease Patients: A Cross-Sectional Study. J Compr Ped. 2024;15(3):e143529. doi: https://doi.org/10.5812/jcp-143529
Siadati A, Sabouni F. Kawasaki Disease (KD) in Iran: A Report of 85 Cases. J Compr Ped. 2007;1(2):. doi:
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