Cover image of the article: peripheral blood leukocytes of mouse Effects of somatic extract and culture filtrate of fusarium solani on

Image Credit:J Inflamm Dis

peripheral blood leukocytes of mouse Effects of somatic extract and culture filtrate of fusarium solani on

Authors

MR Aghamirian,*, F Zaini, H Jahani Hashemi
*Corresponding Author: Email: mraghamirian@mail.com

Journal of Inflammatory Diseases:Vol. 8, issue 3; 14-20
Published online:Dec 31, 2004
Article type:Research Article
How to Cite:Aghamirian M, Zaini F, Jahani Hashemi H. peripheral blood leukocytes of mouse Effects of somatic extract and culture filtrate of fusarium solani on. J Inflamm Dis. 2024;8(3):e155063. doi:

Abstract

¯Abstract Background: The effect of somatic extract and culture filtrate of fusarium solani on peripheral blood leukocyte could be used in pharmacological studies. Objective: The aim of this study was to determine the effect of somatic and culture filtrate of fusarium solani on peripheral blood leukocytes counts in mouse. Methods: Fusarium solani strains UAMH7419 and UAMH3317 were used to prepare the somatic extract and culture filtrate. These substances with or without adjuvant, were injected intraperitoneally. Peripheral blood leukocytes count was then carried out and data were analyzed using non-parametric Mann-Whitney test. Findings: The somatic extract and filtrate culture of F. solani strains UAMH3317 and UAMH7419 induced leukocytosis and lymphocytosis in mouse. Conclusion: Leukocytosis producing effect of fusarium solani strains UAMH7419 and UAMH3317 could be used for therapeutic purposes especially in those with leukopenia although more studies are needed.

Highlights

Copyright

© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.

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