Journal of Inflammatory Diseases
The Official Journal of Qazvin University of Medical Sciences
Molecular Investigation of Resistance to Disinfectants in Acinetobacter Baumannii Isolates Collected From Qazvin Hospitals, Iran (2017)
Authors
Abstract
Background Acinetobacter baumannii is an important agent of nosocomial infections. There are several reports on the presence of disinfectants-resistant Acinetobacter baumannii developed by qacE and qacEΔ1 genes in medical centers. Objective The current study aimed to assess the relevant antimicrobial susceptibility and to determine the frequency of genes encoding resistance to disinfectants in A. baumannii isolates. Methods In the current cross-sectional study, 141 A. baumannii were collected from hospitals in Qazvin Province, Iran. All bacterial isolates were identified using standard laboratory methods and by the presence of the blaOXA-51-like gene. The antimicrobial susceptibility was determined by the standard Kirby- Bauer Test. Furthermore, the presence of qacE and qacEΔ1 genes was investigated using polymerase chain reaction and sequencing techniques. Findings In total, 133 (94.32%) isolates suggested a Multidrug Resistance (MDR) pattern; 84 (59%) and 24 (17%) isolates harbored qacEΔ1 and qacE genes, respectively. There was a significant association between the presence of resistance genes and MDR patterns (P=0.001). Conclusion The obtained results indicated a significant rate of resistance against disinfectants in Acinetobacter baumannii isolates among the studied hospitals; thus, more attention should be paid to the infection control committees of medical centers.
Highlights
Copyright
© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
Similar Articles
Evaluation of Ciprofloxacin (gyrA, parC Genes) and Tetracycline (tetB Gene) Resistance in Nosocomial Acinetobacter baumannii Infections
Nowroozi J, Akhavan Sepahi A, Tahmasebinejad Kamarposhti L, Razavipour R, Mazhar F. Evaluation of Ciprofloxacin (gyrA, parC Genes) and Tetracycline (tetB Gene) Resistance in Nosocomial Acinetobacter baumannii Infections. Jundishapur J Microbiol. 2014;7(2):e8976. doi: https://doi.org/10.5812/jjm.8976
Molecular Identification of Resistance Determinants, Integrons and Genetic Relatedness of Extensively Drug Resistant Acinetobacter baumannii Isolated From Hospitals in Tehran, Iran
Najar Peerayeh S, Karmostaji A. Molecular Identification of Resistance Determinants, Integrons and Genetic Relatedness of Extensively Drug Resistant Acinetobacter baumannii Isolated From Hospitals in Tehran, Iran. Jundishapur J Microbiol. 2015;8(7):e59879. doi: https://doi.org/10.5812/jjm.27021v2
Beta-Lactamase Encoded Genes blaTEM and blaCTX Among Acinetobacter baumannii Species Isolated From Medical Devices of Intensive Care Units in Tehran Hospitals
Khalilzadegan S, Sade M, Godarzi H, Eslami G, Hallajzade M, et al. Beta-Lactamase Encoded Genes blaTEM and blaCTX Among Acinetobacter baumannii Species Isolated From Medical Devices of Intensive Care Units in Tehran Hospitals. Jundishapur J Microbiol. 2016;9(5):e14990. doi: https://doi.org/10.5812/jjm.14990
Antibiotic Resistance Pattern and Prevalence of blaOXA-51, blaNDM, blaVIM, blaPER, blaVEB, blaCTX, tetA and tetB Genes in Acinetobacter baumannii Isolated from Clinical Specimens of Hospitals in Tabriz city, Iran
Jafari Sales A, Naebi S, Bannazadeh-Baghi H, Saki M. Antibiotic Resistance Pattern and Prevalence of blaOXA-51, blaNDM, blaVIM, blaPER, blaVEB, blaCTX, tetA and tetB Genes in Acinetobacter baumannii Isolated from Clinical Specimens of Hospitals in Tabriz city, Iran. J Clin Res Paramed Sci. 2021;10(2):e118521. doi: https://doi.org/10.5812/jcrps.118521
Detection of Carbapenemase Genes in Acinetobacter baumannii Isolates from Al-Azizya Hospital, Wasit, Iraq
Jalil Alawi A, Pourahmad F, Fattahi K. Detection of Carbapenemase Genes in Acinetobacter baumannii Isolates from Al-Azizya Hospital, Wasit, Iraq. Jundishapur J Microbiol. 2025;18(6):e159737. doi: https://doi.org/10.5812/jjm-159737
- Scopus by DOI: 0
Last Update: 2 weeks ago
- Scopus by Title: 0
Last Update: 2 weeks ago
- Scopus by Title (Ref): 5
Last Update: 2 weeks ago
- CrossRef: 0
Last Update: 5 days ago