In this study, we examined the phenomenology of OCD in children and adolescents in Bangladesh and found that 40.6% of patients had a first- degree family history of psychiatric illness. The overall pattern of family history indicated that most patients had anxiety disorder (62%), followed by psychotic illness, and mood disorder. This result suggests a biological basis for OCD and genetic studies that find higher concordance rates of OCD in first- degree family members and twins than in general population (
Table 1) (
1-
4,
11). A recent published study by Chowdhury et al. found similar results in a hospital setting, indicating that 45% of patients had a family history of mental disorders with deviation to OCD (
1). According to CY-BOCS, the pattern indicates that most of the patients had miscellaneous obsessions (70.8%), which mainly included pathological doubt, followed by contamination obsession (69.8%), and religious obsessions (69.8%). These findings are consistent with those of other similar representative studies with variations in percentages of the symptoms; for example, in the study of Chowdhury et al. miscellaneous obsession was lower than 56.7% (
Figure 1) (
1,
12,
13). The variation could be explained by differences in the study setting, as one study was conducted in a hospital setting and another was done in a consultation center. The CY-BOCS pattern of compulsion indicates that most patients had washing/cleaning compulsion, followed by checking compulsion, and miscellaneous obsession; and the findings are in agreement with those of other studies with variations in percentage (
Figure 2) (
12,
13). The present study revealed that comorbidity was present among 45.3% of children and adolescents with OCD, which is in between the widely variable range of other studies (
Table 1) (
1,
2,
4,
6,
11,
14,
15). The pattern of comorbidity also indicated that most patients had hyperkinetic disorder, followed by oppositional defiant disorder, specific phobia, and major depressive disorder comparable to other findings except for the absence of alcohol and drug related disorders and eating disorder, which can be explained by Bangladeshi sociocultural background (
1,
16). Moreover, variations in comorbidity that were found in the study of Chowdhury et al. can also be explained by different study settings. Comorbidity pattern also showed two specific patterns for children and adolescent groups. The proportions of major depressive disorder (15.1%), followed by social phobia (6.1%) and hyperkinetic disorder (6.1%) were higher among the adolescents, whereas hyperkinetic disorder (12.1%), tic disorder (7.3%), and specific phobia (7.3%) were higher among children (
Table 1). This finding is somewhat consistent with other study findings and the differences could be explained by study setting (
1,
2,
4,
6,
11,
16). Considering the caregivers’ perception about the child’s disease, 89.6% believed that it was mental illness, which indicates good awareness among parents of OCD patients. However, we should also keep in mind that most of the parents had good educational and economic background, and the results can be compared with those of the study by Chowdhury et al. which revealed that 88.3% of the participants regarded OCD as a mental illness (
Table 5) (
1). The present study revealed a statistically significant relationship between OCD and the religious practice of the patients (
Table 5); this can be explained by overall religious practices and beliefs of Bangladeshi people. Moreover, similar results were found in another study that assessed the relationship between OCD symptoms and religious practice (
1,
8).
In conclusion, OCD is a poorly studied disorder of children and adolescents in Bangladesh.Miscellaneous and contamination obsessions are prominent as obsessions, whereas checking and miscellaneous obsessions are prominent as compulsions in Bangladesh. Conducting further large scale multi-centered studies would help generalize the study results. Moreover, taking the necessary steps based on the results would reduce the distress and sufferings of children and adolescents.