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Jundishapur Journal of Microbiology
Ahvaz Jundishapur University of Medical Sciences
Antimycobacterial activity of partial purified extract of Allium ascalonicum
Author(s):
1Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences-Department of Medical Microbiology, Ahvaz Jundishapur University of Medical Sciences, [email protected], Iran
2Department of Medical Microbiology, Ahvaz Jundishapur University of Medical Sciences, Iran
*Corresponding Author: Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences-Department of Medical Microbiology, Ahvaz Jundishapur University of Medical Sciences, [email protected], Iran. Email: [email protected]
Published online:Oct 31, 2009
Article type:Research Article
Received:Jun 01, 2009
Accepted:Nov 01, 2009
How to Cite:Amin M, Segatoleslami S, Hashemzadeh M, . Antimycobacterial activity of partial purified extract of Allium ascalonicum. Jundishapur J Microbiol. 2009;2(4):. doi:
Abstract
Introduction and objective: The World Health Organization estimates that about 8 to 10 million new Tuberculosis (TB) cases occur annually worldwide and its incidence is currently increasing. There are two million deaths from TB each year. The plants are an important source of new antimicrobial agents. In this study, antibacterial activity of Allium ascalonicum against Mycobacterium tuberculosis was evaluated.
Materials and methods: To extraction antibacterial agent from this plant, 100g of underground root of A. ascalonicum was mixed with 100ml ethyl acetate and shacked gently. Partially purified antibacterial compound was isolated by organic solvents. Antibacterial activity of this fraction against M. tuberculosis was performed using the E test.
Results: Shallot extract showed antimycobacterial activity with a minimum inhibitory concentration (MIC) value of 500μg/ml.
Conclusion: It is implied that A. ascalonicum extract could be used as an effective antibacterial agent against M. tuberculosis, which is a resistant infection in pulmonary tuberculosis.
Copyright
© 2009, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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