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Jundishapur Journal of Microbiology
Ahvaz Jundishapur University of Medical Sciences
e-ISSN 2008-4161
p-ISSN 2008-3645
The Efficacy of Short-Term vs. Long-Term Antibiotic Therapy in Preventing Deep Infection After Orthopedic Procedures (A Prospective Observational Study)
Authors
1Razi Hospital, Trauma Research Center Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2Orthopedic Surgeon, Boroujerd, Lorestan, IR Iran
*Corresponding Author: Saeid Tabatabaei, Razi Hospital, Trauma Research Center, Jundishapur University of Medical Sciences, Ahvaz, IR Iran. Tel: +98- 6113333050-1, Fax:+98-6113910857, E-mail: Email: saaidt1379@hotmail.com
Published online:Apr 30, 2012
Article type:Research Article
Received:Jun 01, 2011
Accepted:Nov 25, 2011
How to Cite:Khorrami M, Tabatabaei S, Ahmadarabi M. The Efficacy of Short-Term vs. Long-Term Antibiotic Therapy in Preventing Deep Infection After Orthopedic Procedures (A Prospective Observational Study). Jundishapur J Microbiol. 2012;5(2):. doi: https://doi.org/10.5812/jjm.3521
Abstract
Background: Antibiotic therapy prevents postoperative infections after orthopedic procedures, but the method and prescribed dose of this therapy are debated. Short-term prophylaxis and long-term prophylaxis are 2 accepted methods after orthopedic procedures.
Objectives: In this prospective observational study, we compared the results of short-term and long-term prophylaxis after elective orthopedic procedures at 2 hospitals of Jundishapur University of Medical Sciences.
Patients and Methods: We divided patients who underwent uneventful orthopedic operations into 2 groups, administered short- and long-term prophylactic antibiotic therapy, respectively, and observed the patients for signs and symptoms of superficial and deep infections. We compared and analyzed the results with SPSS, considering P values of less than 0.001 to indicate a significant difference.
Results: There was no significant difference regarding superficial and deep infections between short- and long-term prophylaxis groups; thus, both methods can be used for prophylaxis after elective orthopedic surgeries, effecting equal rates of success.
Conclusions: Short-term prophylaxis can be used for clean orthopedic procedures with equivalent results as long-term therapy.
Copyright © 2012 Kowsar Corp. All rights reserved.
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Copyright
© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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