Fulltext
Full text is available in PDF
Jundishapur Journal of Microbiology
Ahvaz Jundishapur University of Medical Sciences
The Efficacy of Short-Term vs. Long-Term Antibiotic Therapy in Preventing Deep Infection After Orthopedic Procedures (A Prospective Observational Study)
Author(s):
1Razi Hospital, Trauma Research Center Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2Orthopedic Surgeon, Boroujerd, Lorestan, IR Iran
*Corresponding Author: Saeid Tabatabaei, Razi Hospital, Trauma Research Center, Jundishapur University of Medical Sciences, Ahvaz, IR Iran. Tel: +98- 6113333050-1, Fax:+98-6113910857, E-mail: Email: [email protected]
Published online:Apr 30, 2012
Article type:Research Article
Received:Jun 01, 2011
Accepted:Nov 25, 2011
How to Cite:Khorrami M, Tabatabaei S, Ahmadarabi M. The Efficacy of Short-Term vs. Long-Term Antibiotic Therapy in Preventing Deep Infection After Orthopedic Procedures (A Prospective Observational Study). Jundishapur J Microbiol. 2012;5(2):. doi: https://doi.org/10.5812/jjm.3521
Abstract
Background: Antibiotic therapy prevents postoperative infections after orthopedic procedures, but the method and prescribed dose of this therapy are debated. Short-term prophylaxis and long-term prophylaxis are 2 accepted methods after orthopedic procedures.
Objectives: In this prospective observational study, we compared the results of short-term and long-term prophylaxis after elective orthopedic procedures at 2 hospitals of Jundishapur University of Medical Sciences.
Patients and Methods: We divided patients who underwent uneventful orthopedic operations into 2 groups, administered short- and long-term prophylactic antibiotic therapy, respectively, and observed the patients for signs and symptoms of superficial and deep infections. We compared and analyzed the results with SPSS, considering P values of less than 0.001 to indicate a significant difference.
Results: There was no significant difference regarding superficial and deep infections between short- and long-term prophylaxis groups; thus, both methods can be used for prophylaxis after elective orthopedic surgeries, effecting equal rates of success.
Conclusions: Short-term prophylaxis can be used for clean orthopedic procedures with equivalent results as long-term therapy.
Copyright © 2012 Kowsar Corp. All rights reserved.
Copyright
© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
14
Oct
2021
Implementing the Protocol of Perioperative Narrow-spectrum Antibiotic Prophylaxis in the Surgical Wards of Mofid Children’s Hospital in 2019 - 2020, A Comparative Study
Seyed Alireza Fahimzad,
Bahador Mirrahimi,
Farideh Shiva,
Niloofar Esfahanian,
Seyyedeh Azam Mousavizadeh,
Fariba Shirvani
Fahimzad SA, Mirrahimi B, Shiva F, Esfahanian N, Mousavizadeh SA, et al. Implementing the Protocol of Perioperative Narrow-spectrum Antibiotic Prophylaxis in the Surgical Wards of Mofid Children’s Hospital in 2019 - 2020, A Comparative Study. Arch Pediatr Infect Dis. 2022;10(1):e115402. doi: https://doi.org/10.5812/pedinfect.115402
4
Mar
2018
Evaluation of Antibiotic Prophylaxis Administration at the General and Neuro-Surgery Ward of a Teaching Hospital in Tehran, Iran
Nazanin Rahmanian,
Hadi Mirhashemi,
Mehdi Rajabi,
Mohammad Parvizi,
Zahra Sahraei
Rahmanian N, Mirhashemi H, Rajabi M, Parvizi M, Sahraei Z. Evaluation of Antibiotic Prophylaxis Administration at the General and Neuro-Surgery Ward of a Teaching Hospital in Tehran, Iran. J Rep Pharm Sci. 2018;7(2):e147574. doi:
6
Sep
2015
The Efficacy of Long-Term Post-Operative Antibiotic Therapy Versus Placebo on Dental Implants
Neda Moslemi,
Zahra Karami,
Aysan Shahnaz Miandoab,
Samane Masoumi,
Yadollah Soleimani Shayesteh,
Abbas Karimi
,et al.Moslemi N, Karami Z, Shahnaz Miandoab A, Masoumi S, Soleimani Shayesteh Y, et al. The Efficacy of Long-Term Post-Operative Antibiotic Therapy Versus Placebo on Dental Implants. Thrita J Neu. 2015;4(3):e30678. doi: https://doi.org/10.5812/thrita.30678
1
Nov
2014
Antibiotics Use Patterns for Surgical Prophylaxis Site Infection in Different Surgical Wards of a Teaching Hospital in Ahvaz, Iran
Seyed Mohammad Alavi,
Fatemeh Roozbeh,
Farzaneh Behmanesh,
Leila Alavi
Alavi SM, Roozbeh F, Behmanesh F, Alavi L. Antibiotics Use Patterns for Surgical Prophylaxis Site Infection in Different Surgical Wards of a Teaching Hospital in Ahvaz, Iran. Jundishapur J Microbiol. 2014;7(11):e12251. doi: https://doi.org/10.5812/jjm.12251
30
Dec
2024
Evaluation of Surgical Antibiotic Prophylaxis Guideline Adherence: A Cross-Sectional Study of Two Iranian Teaching Hospitals
Maryam Farasatinasab,
Azadeh La'li,
Asma Zibafard,
Mohsen Khaleghian,
Somayyeh Nasiripour,
Hamidreza Alizadeh Otaghvar
,et al.Farasatinasab M, La'li A, Zibafard A, Khaleghian M, Nasiripour S, et al. Evaluation of Surgical Antibiotic Prophylaxis Guideline Adherence: A Cross-Sectional Study of Two Iranian Teaching Hospitals. Arch Clin Infect Dis. 2025;20(2):e148269. doi: https://doi.org/10.5812/archcid-148269
Download PDF544.76 KB
Crossmark
Checking
Comments
Number of Comments:0Cited by
- Scopus by DOI: 1
Last Update: 2 weeks ago
- Scopus by Title: 1
Last Update: 2 weeks ago
- Scopus by Title (Ref): 1
Last Update: 2 weeks ago
- CrossRef: 1
Last Update: 4 days ago
Ordering Reprints
Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC
Search Relations
Author(s):
Related Articles