Jundishapur Journal of Natural Pharmaceutical Products
The Official Journal of Ahvaz Jundishapur University of Medical Sciences
DISTRIBUTION MODEL OF SERUM LIPOPROTEIN (A) CONCENTRATION IN A HEALTHY IRANIAN POPULATION LIVING IN KHUZESTAN PROVINCE, IRAN. 2004.
Authors
Abstract
Based on many epidemiologic studies, lipoprotein (a) [Lp(a)] with its peculiar structural properties was proposed as independent, risk factor for cardiovascular and thrombotic cerebral events. Since, genetic effect plays a paramount role in determining the final serum concentration, the reference serum concentration for this particle exhibits a wide variation among different population and even within a family. In order to prevent its pathologic effect which has been related to its high serum concentration it is a prerequisite to determine its serum concentration distribution model in a particular population before any therapeutic measure is arranged. To accomplish this goal a group of 350 healthy volunteers living in southern province of Khuzestan, Iran, were analyzed for their Lp (a) serum concentration employing and isoform- insensitive ELISA technique. The obtained result showed skewed distribution toward lower concentration ranging from 3 to 53 mg/dL with mean, median and standard deviation as 14.42, 12.0 and 8.46 mg/dL.
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Copyright
© 2007, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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